DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33465 and CG33226

DIOPT Version :9

Sequence 1:	NP_001033950.2	Gene:	CG33465 / 3885587	FlyBaseID:	FBgn0053465	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	NP_995917.3	Gene:	CG33226 / 2768859	FlyBaseID:	FBgn0069056	Length:	292	Species:	Drosophila melanogaster

Alignment Length:	296	Identity:	92/296 - (31%)
Similarity:	140/296 - (47%)	Gaps:	44/296 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSRVLSLALIGLVLCQGLAQ-LLDKKCHDPKTS--ENINFNHGA-TETAPWMASIYKNNQFICDG 61
            |..:|...::.|...:.|.| |||..|......  |.|...|.| .:..|||..|.:.....|.|
  Fly    10 MKWLLVCFILALRSYESLGQDLLDPNCVQTPVGVREQILGGHNADIKLHPWMVQILQRGYHFCGG 74

  Fly    62 TLVHKLFVLTAASCISKDSQLYVLFGMYN----QYRDASQFFNNEQYGVAVALQ----HSNFRPN 118
            :|:..|||||||.|.|: .:|.|.||.|:    :|..:||:.:  .:|..:.::    ||::|..
  Fly    75 SLISSLFVLTAAHCHSR-YRLKVRFGRYSGITPRYLCSSQYCS--PFGPEIDVKRIFLHSSYRDY 136

  Fly   119 NGVNDIGLLRLYGEVTHYAHIRPICII-----------LDHVVKSAPFERFEGFGWQQQGTEASS 172
            :.. ||.|..|...|.:....||||::           |::|.      .|...||.:..::.:|
  Fly   137 HNY-DIALFLLAKPVRYNVQTRPICVLQTSNKDKLRQFLNYVA------MFNVTGWGKTESQLTS 194

  Fly   173 QVRQTVYLSQKKPFECHRN--GQLLPINEG--QFCAGNRDRSFCRSNSGSPLTADFTY-GVKNIT 232
            .:.||..|     |...|.  .|:.....|  ..|||:...|.|..:||.||:|:.|: |||. |
  Fly   195 TILQTTSL-----FHLDRKFCAQIFDRKIGWPHICAGHSQSSTCTGDSGGPLSAELTFSGVKR-T 253

  Fly   233 VQVGLVSYGSELCSPTSVYTDVVAFKDWIYNTVRNF 268
            |..|::|||:..|...:|:|:|:.:.:||.:.|.||
  Fly   254 VLFGIISYGAPNCREVTVFTNVLRYSNWIRDIVHNF 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33465	NP_001033950.2	Tryp_SPc	46..264	CDD:238113	76/241 (32%)
		Tryp_SPc	46..261	CDD:214473	74/238 (31%)
		Tryp_SPc	293..484	CDD:304450
		Tryp_SPc	293..481	CDD:214473
CG33226	NP_995917.3	Tryp_SPc	47..285	CDD:238113	79/253 (31%)
CG33226	NP_995917.3	Tryp_SPc	47..282	CDD:214473	77/250 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	102	1.000	Domainoid score	I4289
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	108	1.000	Inparanoid score	I3480
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000404
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_108863
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.860