DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33465 and Klk8

DIOPT Version :9

Sequence 1:	NP_001033950.2	Gene:	CG33465 / 3885587	FlyBaseID:	FBgn0053465	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	NP_001311327.1	Gene:	Klk8 / 259277	MGIID:	1343327	Length:	260	Species:	Mus musculus

Alignment Length:	284	Identity:	76/284 - (26%)
Similarity:	118/284 - (41%)	Gaps:	70/284 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 ALIGLVLCQGLAQLLDKKCHDPKTSENINFNHGATETAPWMASIYKNNQFICDGTLVHKLFVLTA 72
            |..||...||...|..::|              ...:.||.|::::..:.||.|.||...:||||
Mouse    21 AWAGLTRAQGSKILEGREC--------------IPHSQPWQAALFQGERLICGGVLVGDRWVLTA 71

  Fly    73 ASCISKDSQLYVLFGMYN-QYRDASQFFNNEQYGVAVALQH---SNFRPNNGVNDIGLLRLYGEV 133
            |.|  |..:..|..|.:: |.||..:    ::..||.::||   :|..|.:..:||.|:||....
Mouse    72 AHC--KKQKYSVRLGDHSLQSRDQPE----QEIQVAQSIQHPCYNNSNPEDHSHDIMLIRLQNSA 130

  Fly   134 THYAHIRPI------------CIILDHVVKSAPFERFEGFGWQQQGTEASSQVR--QTVYLSQKK 184
            .....::|:            |||               .||   ||..|.|..  .|:..::.|
Mouse   131 NLGDKVKPVQLANLCPKVGQKCII---------------SGW---GTVTSPQENFPNTLNCAEVK 177

  Fly   185 PFECHRNGQLLP--INEGQFCAGNRD-RSFCRSNSGSPLTADFTYGVKNITVQVGLVSYGSELC- 245
            .:..::..:..|  |.||..|||:.: ...|:.:||.||..|   |:..     |:.|:||:.|
Mouse   178 IYSQNKCERAYPGKITEGMVCAGSSNGADTCQGDSGGPLVCD---GMLQ-----GITSWGSDPCG 234

  Fly   246 --SPTSVYTDVVAFKDWIYNTVRN 267
              ....|||.:..:..||..|:.|
Mouse   235 KPEKPGVYTKICRYTTWIKKTMDN 258

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33465	NP_001033950.2	Tryp_SPc	46..264	CDD:238113	67/241 (28%)
		Tryp_SPc	46..261	CDD:214473	65/238 (27%)
		Tryp_SPc	293..484	CDD:304450
		Tryp_SPc	293..481	CDD:214473
Klk8	NP_001311327.1	Tryp_SPc	32..252	CDD:214473	67/265 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910