DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG33465 and CG30289

DIOPT Version :9

Sequence 1:	NP_001033950.2	Gene:	CG33465 / 3885587	FlyBaseID:	FBgn0053465	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	NP_726081.1	Gene:	CG30289 / 246532	FlyBaseID:	FBgn0050289	Length:	316	Species:	Drosophila melanogaster

Alignment Length:	319	Identity:	92/319 - (28%)
Similarity:	148/319 - (46%)	Gaps:	57/319 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 ALIGLVLCQGLA------QLLDKKCHDPKTSENINFNHGATET----APWMASIYKNNQFICDGT 62
            |:|..::|..:|      :||.:.|...|....:....|..:|    .|||..::.:..  |.|:
  Fly     6 AVIAALVCLFIANNNVMSRLLVENCGISKDDPYVPNIFGGAKTNIQENPWMVLVWSSKP--CGGS 68

  Fly    63 LVHKLFVLTAASCISKDSQLYVLFGMYNQYRDASQFFNN----EQYGVAVALQ--HSNFRPNNGV 121
            |:.:.||||||.|:|.: .|||..|.|..........||    :.|.::|.::  |.|:   ||:
  Fly    69 LIARQFVLTAAHCVSFE-DLYVRLGDYETLDPMPYCLNNHCIPKFYNISVDMKIVHENY---NGI 129

  Fly   122 ---NDIGLLRLYGEVTHYAHIRPICIILDHVVKSAPFERFEGFGWQQQGTEASSQVRQTVYLSQK 183
               |||.|||:...|.:..::||||:::...::|.|.....|:|..:.|..:...:..|:|....
  Fly   130 TLQNDIALLRMSEAVEYSDYVRPICLLVGEQMQSIPMFTVTGWGETEYGQFSRILLNATLYNMDI 194

  Fly   184 KPFECHRNGQLLPINEGQFCAGNRDRSFCRSNSGSPLTADFTYGVKNITVQVGLVSYGSELCSP- 247
            .......|.|   .:..|.|||:...:.|:.:||.||::.|.||.:.::.|.||||||||.|:.
  Fly   195 SYCNIKFNKQ---ADRSQICAGSHTSNTCKGDSGGPLSSKFHYGNRLLSFQYGLVSYGSERCAAN 256

  Fly   248 -TSVYTDVVAFKDWIYN---------------------------TVRNFETKGDQVVYE 278
             ..|||:|...::||:|                           .:||.|...:::|||
  Fly   257 VAGVYTNVSYHREWIFNKMVQFKPTGHTTFWLSKLVGQTCNITDIIRNIELMYNRIVYE 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33465	NP_001033950.2	Tryp_SPc	46..264	CDD:238113	76/255 (30%)
		Tryp_SPc	46..261	CDD:214473	73/225 (32%)
		Tryp_SPc	293..484	CDD:304450
		Tryp_SPc	293..481	CDD:214473
CG30289	NP_726081.1	Tryp_SPc	42..271	CDD:214473	75/237 (32%)
CG30289	NP_726081.1	Tryp_SPc	42..271	CDD:238113	75/237 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	102	1.000	Domainoid score	I4289
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	108	1.000	Inparanoid score	I3480
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000404
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_108863
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.860