DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33465 and CG30090

DIOPT Version :9

Sequence 1:	NP_001033950.2	Gene:	CG33465 / 3885587	FlyBaseID:	FBgn0053465	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	NP_725487.1	Gene:	CG30090 / 246448	FlyBaseID:	FBgn0050090	Length:	291	Species:	Drosophila melanogaster

Alignment Length:	283	Identity:	98/283 - (34%)
Similarity:	142/283 - (50%)	Gaps:	26/283 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSRVLSLALIGLVLCQGLAQLLDKKCHDPKTSENINF-----NHGATETAPWMASIYKNNQFICD 60
            ::.:.:|| ||::...|..:.|:.:|  ..|:..|.|     ......:.||||.|:.:.:.||.
  Fly     5 IAAITALA-IGVLCSLGNGEYLEPRC--GLTANTIAFKIIGGRDAIINSNPWMAYIHSSVKLICG 66

  Fly    61 GTLVHKLFVLTAASCISKDSQLYVLFGMYNQYRDASQFFNN-------EQYGVAVALQHSNFRPN 118
            |||:.:.||||||.|:::.|.:.|..|.|:.  .|::..|:       |::.|.:|.:|..|...
  Fly    67 GTLITQRFVLTAAHCVNEGSAVKVRLGEYDD--TATEDCNSKICIPRAEEHDVDMAFRHGKFSEI 129

  Fly   119 NGVNDIGLLRLYGEVTHYAHIRPICIILD----HVVKSAPFERFEGFGWQQQGTEASSQVRQTVY 179
            ..:|||.||||...||..|||.||||||.    .:|.|  .|.|...||.:..|..:..|.|...
  Fly   130 KNLNDIALLRLAKFVTFKAHISPICIILGTSKRELVDS--IEWFVATGWGETRTHRTRGVLQITQ 192

  Fly   180 LSQKKPFECHRN-GQLLPINEGQFCAGNRDRSFCRSNSGSPLTADFTYGVKNITVQVGLVSYGSE 243
            |.:....:|.:. |:|  :.:.|.|||......|..:||.||.....:..|...||.|:|||||.
  Fly   193 LQRYNSSQCMQALGRL--VQQNQICAGRLGSDTCNGDSGGPLFQTVRHMDKMRPVQFGVVSYGSR 255

  Fly   244 LCSPTSVYTDVVAFKDWIYNTVR 266
            .||...|||||.::.|||...|:
  Fly   256 ECSGIGVYTDVYSYADWIATVVQ 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33465	NP_001033950.2	Tryp_SPc	46..264	CDD:238113	87/229 (38%)
		Tryp_SPc	46..261	CDD:214473	85/226 (38%)
		Tryp_SPc	293..484	CDD:304450
		Tryp_SPc	293..481	CDD:214473
CG30090	NP_725487.1	Tryp_SPc	39..273	CDD:214473	85/239 (36%)
CG30090	NP_725487.1	Tryp_SPc	40..276	CDD:238113	87/241 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463446
Domainoid	1	1.000	102	1.000	Domainoid score	I4289
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	108	1.000	Inparanoid score	I3480
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000404
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_108863
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.890