DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG33465 and F12

DIOPT Version :9

Sequence 1:NP_001033950.2 Gene:CG33465 / 3885587 FlyBaseID:FBgn0053465 Length:488 Species:Drosophila melanogaster
Sequence 2:NP_000496.2 Gene:F12 / 2161 HGNCID:3530 Length:615 Species:Homo sapiens


Alignment Length:242 Identity:66/242 - (27%)
Similarity:107/242 - (44%) Gaps:43/242 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly    46 PWMASIYKNNQFICDGTLVHKLFVLTAASCIS---KDSQLYVLFGM--YNQYRDASQFFNNEQYG 105
            |::|::|..:.| |.|:|:...:|||||.|:.   ....|.|:.|.  .|...:..|......|.
Human   385 PYIAALYWGHSF-CAGSLIAPCWVLTAAHCLQDRPAPEDLTVVLGQERRNHSCEPCQTLAVRSYR 448

  Fly   106 VAVALQHSNFRPNNGVNDIGLLRLYGEVTHYA-----HIRPICIILDHVVKSAPFE----RFEGF 161
            :     |..|.|.:..:|:.||||..:.....     :::|:|:...   .:.|.|    :..|:
Human   449 L-----HEAFSPVSYQHDLALLRLQEDADGSCALLSPYVQPVCLPSG---AARPSETTLCQVAGW 505

  Fly   162 GWQQQGTEASS---QVRQTVYLSQKKPFECH----RNGQLLPINEGQFCAG--NRDRSFCRSNSG 217
            |.|.:|.|..:   |..|..:||.::   |.    ....:||   |..|||  ......|:.:||
Human   506 GHQFEGAEEYASFLQEAQVPFLSLER---CSAPDVHGSSILP---GMLCAGFLEGGTDACQGDSG 564

  Fly   218 SPLTADFTYGVKNITVQVGLVSYGSELC---SPTSVYTDVVAFKDWI 261
            .||..:.....:.:|:| |::|:||. |   :...|||||..:..||
Human   565 GPLVCEDQAAERRLTLQ-GIISWGSG-CGDRNKPGVYTDVAYYLAWI 609

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG33465NP_001033950.2 Tryp_SPc 46..264 CDD:238113 66/242 (27%)
Tryp_SPc 46..261 CDD:214473 64/240 (27%)
Tryp_SPc 293..484 CDD:304450
Tryp_SPc 293..481 CDD:214473
F12NP_000496.2 FN2 41..88 CDD:128373
EGF_CA 96..131 CDD:238011
FN1 133..173 CDD:238018
EGF 178..206 CDD:278437
Kringle 217..295 CDD:278480
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 298..359
Tryp_SPc 372..609 CDD:214473 64/240 (27%)
Tryp_SPc 373..612 CDD:238113 66/242 (27%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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