DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33465 and CELA1

DIOPT Version :9

Sequence 1:	NP_001033950.2	Gene:	CG33465 / 3885587	FlyBaseID:	FBgn0053465	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	NP_001962.3	Gene:	CELA1 / 1990	HGNCID:	3308	Length:	258	Species:	Homo sapiens

Alignment Length:	270	Identity:	71/270 - (26%)
Similarity:	107/270 - (39%)	Gaps:	60/270 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 PKTSENINFNHGATETA--PWMASI---YK---NNQFICDGTLVHKLFVLTAASCISKDSQLYVL 85
            |:|:..:   .|.||..  .|.:.|   |:   :....|.|||:.:.:|:|||.|:.......|:
Human    13 PETNARV---VGGTEAGRNSWPSQISLQYRSGGSRYHTCGGTLIRQNWVMTAAHCVDYQKTFRVV 74

  Fly    86 FGMYNQYRDASQFFNNEQY-GVAVALQHSNFRPNN--GVNDIGLLRLYGEVTHYAHIR------- 140
            .|.:|    .||....||| .|...:.|..:..:|  ...||.||||...||..::::
Human    75 AGDHN----LSQNDGTEQYVSVQKIVVHPYWNSDNVAAGYDIALLRLAQSVTLNSYVQLGVLPQE 135

  Fly   141 --------PICIILDHVVKSAPFERFEGFGWQQQGTEASSQVRQTV---YLSQKKPFECHRNGQL 194
                    | |.|.               ||.:  |:.:.|:.||:   ||.......|..:...
Human   136 GAILANNSP-CYIT---------------GWGK--TKTNGQLAQTLQQAYLPSVDYAICSSSSYW 182

  Fly   195 -LPINEGQFCAGNRD-RSFCRSNSGSPL--TADFTYGVKNITVQVGLVSYGSELCSPTSVYTDVV 255
             ..:.....|||... ||.|:.:||.||  ..:..|.|..:|..|.  |.|..:....:|:|.|.
Human   183 GSTVKNTMVCAGGDGVRSGCQGDSGGPLHCLVNGKYSVHGVTSFVS--SRGCNVSRKPTVFTQVS 245

  Fly   256 AFKDWIYNTV 265
            |:..||.|.:
Human   246 AYISWINNVI 255

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33465	NP_001033950.2	Tryp_SPc	46..264	CDD:238113	65/248 (26%)
		Tryp_SPc	46..261	CDD:214473	63/245 (26%)
		Tryp_SPc	293..484	CDD:304450
		Tryp_SPc	293..481	CDD:214473
CELA1	NP_001962.3	Tryp_SPc	19..254	CDD:238113	68/261 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910