DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33465 and try-3

DIOPT Version :9

Sequence 1:	NP_001033950.2	Gene:	CG33465 / 3885587	FlyBaseID:	FBgn0053465	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	NP_001367393.1	Gene:	try-3 / 183420	WormBaseID:	WBGene00006621	Length:	313	Species:	Caenorhabditis elegans

Alignment Length:	291	Identity:	71/291 - (24%)
Similarity:	118/291 - (40%)	Gaps:	54/291 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 LVLC------QGLAQLLDKKCHDPKTSENINFNHGATETAPWMASI--YKNN--QFICDGTLVHK 66
            ||||      ...|..|.::.:.|..|..|...:...:.|.|||.:  |.:|  ..:|..|::..
Worm     9 LVLCFVFITKHSNAINLCEESYKPIFSFRIIGGNSIDDGANWMAKLVSYGDNGQGILCGATVIDD 73

  Fly    67 LFVLTAASC---ISKDSQLYVLFGMYNQYRDASQFFNNEQYGVAVALQHSNFRPNNGVNDIGLLR 128
            .:::|||.|   :...|.:||.....|:.|         .:.|..|..||.:......|||.|||
Worm    74 FWLVTAAHCALQLQTRSFVYVREPKNNRER---------SFSVKEAYIHSGYNNQTADNDIALLR 129

  Fly   129 LYGEVTHYAHIRPICIILDHVVKSAPFERFE-----GFGWQQQGTEAS-------SQVRQTVYLS 181
            :..:::... |:|:|::.|   .|...::::     |:| ...|.::|       ||..|:..:.
Worm   130 ISSDLSKLG-IKPVCLVHD---DSKLLKQYKNGVVIGYG-LTLGEDSSGEPKLINSQTLQSTSVP 189

  Fly   182 QKKPFECHRNGQLL-----PINEGQFCAGNRDRSFCRSNSGSPLTADFTYGVKNITVQVGLVSYG 241
            .....:|.:..:.|     .|...|.|||.........:||.||....:.|.   .||:|:.|||
Worm   190 IISDDDCVKTWRFLSLLSVKITGYQICAGAYLHGTAPGDSGGPLLIHKSNGE---YVQIGITSYG 251

  Fly   242 SELCSPT-------SVYTDVVAFKDWIYNTV 265
            ::.....       .|||.:..:..||...:
Worm   252 ADGLDGVIDQGKFPGVYTRISKYVPWIQGVI 282

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33465	NP_001033950.2	Tryp_SPc	46..264	CDD:238113	61/248 (25%)
		Tryp_SPc	46..261	CDD:214473	59/245 (24%)
		Tryp_SPc	293..484	CDD:304450
		Tryp_SPc	293..481	CDD:214473
try-3	NP_001367393.1	Tryp_SPc	38..279	CDD:238113	62/257 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	102	1.000	Domainoid score	I4289
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	108	1.000	Inparanoid score	I3480
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_108863
Panther	1	1.100	-	-	O	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.960