DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33465 and F2

DIOPT Version :9

Sequence 1:	NP_001033950.2	Gene:	CG33465 / 3885587	FlyBaseID:	FBgn0053465	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	NP_034298.1	Gene:	F2 / 14061	MGIID:	88380	Length:	618	Species:	Mus musculus

Alignment Length:	292	Identity:	73/292 - (25%)
Similarity:	115/292 - (39%)	Gaps:	48/292 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 GLAQLLDKKCHDPKTSENINFNH----------GATETAPWMASIYKNN--QFICDGTLVHKLFV 69
            ||..|.:||.....|.:.:..::          .....|||...:::.:  :.:|..:|:...:|
Mouse   334 GLRPLFEKKSLKDTTEKELLDSYIDGRIVEGWDAEKGIAPWQVMLFRKSPQELLCGASLISDRWV 398

  Fly    70 LTAASCI--------SKDSQLYVLFGMYNQYRDASQFFNNEQYGVAVAL---QHSNFRPNNGVND 123
            ||||.||        ..::.|.|..|.:::.|...   |.|:..:...:   ...|:|.|.. .|
Mouse   399 LTAAHCILYPPWDKNFTENDLLVRIGKHSRTRYER---NVEKISMLEKIYVHPRYNWRENLD-RD 459

  Fly   124 IGLLRLYGEVTHYAHIRPICIILDHVVKS---APFE-RFEGFG-----WQQQGTEASSQVRQTVY 179
            |.||:|...|....:|.|:|:.....|.|   |.:: |..|:|     |.....|....|.|.|.
Mouse   460 IALLKLKKPVPFSDYIHPVCLPDKQTVTSLLRAGYKGRVTGWGNLRETWTTNINEIQPSVLQVVN 524

  Fly   180 LSQKKPFECHRNGQLLPINEGQFCAG-----NRDRSFCRSNSGSPLTADFTYGVKNITVQVGLVS 239
            |...:...|..:.: :.|.:..||||     .:....|..:||.|......:  .|...|:|:||
Mouse   525 LPIVERPVCKASTR-IRITDNMFCAGFKVNDTKRGDACEGDSGGPFVMKSPF--NNRWYQMGIVS 586

  Fly   240 YGSELC---SPTSVYTDVVAFKDWIYNTVRNF 268
            :| |.|   .....||.|...|.||...:..|
Mouse   587 WG-EGCDRKGKYGFYTHVFRLKRWIQKVIDQF 617

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33465	NP_001033950.2	Tryp_SPc	46..264	CDD:238113	65/247 (26%)
		Tryp_SPc	46..261	CDD:214473	63/244 (26%)
		Tryp_SPc	293..484	CDD:304450
		Tryp_SPc	293..481	CDD:214473
F2	NP_034298.1	GLA	25..89	CDD:214503
		KR	107..189	CDD:214527
		KR	213..295	CDD:214527
		Thrombin_light	313..360	CDD:286482	6/25 (24%)
		Tryp_SPc	360..610	CDD:214473	64/257 (25%)
		Tryp_SPc	361..613	CDD:238113	66/259 (25%)
		High affinity receptor-binding region which is also known as the TP508 peptide. /evidence=ECO:0000250	548..570		6/21 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910