DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33465 and Egfbp2

DIOPT Version :9

Sequence 1:	NP_001033950.2	Gene:	CG33465 / 3885587	FlyBaseID:	FBgn0053465	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	NP_034245.3	Gene:	Egfbp2 / 13647	MGIID:	95292	Length:	261	Species:	Mus musculus

Alignment Length:	247	Identity:	60/247 - (24%)
Similarity:	101/247 - (40%)	Gaps:	53/247 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 PWMASIYKNNQFICDGTLVHKLFVLTAASCISKDSQLYVLFGMYNQYRDASQFFNNEQYG----V 106
            ||..::|...:.||.|.|:.:.:|||||.|       ||  ..|..:...::.|..|...    |
Mouse    37 PWQVAVYYQKEHICGGVLLDRNWVLTAAHC-------YV--DQYEVWLGKNKLFQEEPSAQHRLV 92

  Fly   107 AVALQHSNFRPN-----------NGVNDIGLLRLY--GEVTHYAHIRPICIILDHVVKSAPFERF 158
            :.:..|..|..:           :..||:.||||.  .::|..  ::||.:   ...:..|..:.
Mouse    93 SKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDV--VKPIAL---PTKEPKPGSKC 152

  Fly   159 EGFGWQQQGTEASSQVR-----QTVYLSQKKPFECHRNGQLLPINEGQFCAGNR--DRSFCRSNS 216
            ...||   |:...::.:     |.|:::......|.: ..|..:.:...|||..  .:..||.:|
Mouse   153 LASGW---GSITPTRWQKPDDLQCVFITLLPNENCAK-VYLQKVTDVMLCAGEMGGGKDTCRDDS 213

  Fly   217 GSPLTADFTYGVKNITVQVGLVSYGSELCSP---TSVYTDVVAFKDWIYNTV 265
            |.||..|   |:..     |..|||...|..   .::||:::.|..||.:|:
Mouse   214 GGPLICD---GILQ-----GTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTM 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33465	NP_001033950.2	Tryp_SPc	46..264	CDD:238113	59/244 (24%)
		Tryp_SPc	46..261	CDD:214473	57/241 (24%)
		Tryp_SPc	293..484	CDD:304450
		Tryp_SPc	293..481	CDD:214473
Egfbp2	NP_034245.3	Tryp_SPc	24..253	CDD:214473	57/241 (24%)
Egfbp2	NP_034245.3	Tryp_SPc	25..256	CDD:238113	59/244 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910