DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33465 and CLIPA2

DIOPT Version :9

Sequence 1:	NP_001033950.2	Gene:	CG33465 / 3885587	FlyBaseID:	FBgn0053465	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	XP_320727.4	Gene:	CLIPA2 / 1280859	VectorBaseID:	AGAP011790	Length:	503	Species:	Anopheles gambiae

Alignment Length:	252	Identity:	64/252 - (25%)
Similarity:	113/252 - (44%)	Gaps:	34/252 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 PWMASIYK--NNQFICDGTLVHKLFVLTAASCIS----KDSQLYVLFGMYNQYRDASQFFNNEQY 104
            |||.::::  ..::.|:|.|:....:||.|.|::    :.:.:.|.||.:|...........|..
Mosquito   250 PWMVALFQLPEQRYCCNGALIDPKAILTTAHCVTNCGGRAANIMVRFGEWNMSSTHEMAIPREDI 314

  Fly   105 GVAVALQHSNFRPNNGVNDIGLLRLYGEVTHYAHIRPICIILDHVVKSA--PFERFE-----GFG 162
            ||....||..:.|:..:|:|.:|.|...|.:.|.|:|:|:      .||  |....|     |:|
Mosquito   315 GVKSVHQHPRYSPSALLNNIAVLELAHPVQYQATIQPVCL------PSANQPLRAMENMIATGWG 373

  Fly   163 WQQQGTEASSQVRQTVYLSQKKPFECH------RNGQLLPINEGQFCA----GNRDRSFCRSNSG 217
            ...:.....:|:.:.:.|.:.:|..|.      |......::....|:    |:::|. |..::|
Mosquito   374 RVMEENAPPTQILKRLDLQRMEPSICREALRRVRRPYPFILDSSFVCSTTNHGDQERP-CDGDAG 437

  Fly   218 SPLTADFTYGVKNITVQVGLVSYG---SELCSPTSVYTDVVAFKDWIYNTVRNFETK 271
            :|:..:.. |..|.....||||:|   .:...|.:|.|.||.|::||...|..|:.|
Mosquito   438 APVVVELP-GTTNRYYLHGLVSWGYGCHQKQIPYTVLTKVVHFREWIDRIVLGFKKK 493

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33465	NP_001033950.2	Tryp_SPc	46..264	CDD:238113	61/243 (25%)
		Tryp_SPc	46..261	CDD:214473	59/240 (25%)
		Tryp_SPc	293..484	CDD:304450
		Tryp_SPc	293..481	CDD:214473
CLIPA2	XP_320727.4	Tryp_SPc	244..486	CDD:238113	61/243 (25%)
CLIPA2	XP_320727.4	Tryp_SPc	244..483	CDD:214473	59/240 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910