DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33465 and AgaP_AGAP009252

DIOPT Version :9

Sequence 1:	NP_001033950.2	Gene:	CG33465 / 3885587	FlyBaseID:	FBgn0053465	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	XP_320033.4	Gene:	AgaP_AGAP009252 / 1280210	VectorBaseID:	AGAP009252	Length:	460	Species:	Anopheles gambiae

Alignment Length:	268	Identity:	58/268 - (21%)
Similarity:	100/268 - (37%)	Gaps:	54/268 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 LDKKCHDPKTSENINFNHGATETA----PWMASI-YKNN-----QFICDGTLVHKLFVLTAASCI 76
            ||:..|..|.|.. :.|....||.    |::..: ::.|     |:.|.|||:....|||:|.|:
Mosquito   221 LDECAHRIKASSG-STNEAQFETGYISEPYLVEVGWRGNGDAKAQWSCRGTLITSKAVLTSAKCL 284

  Fly    77 SKDS--QLYVLFGMYNQYRDASQFFNNEQYGVAVALQHSNFRPNNGVNDIGLLRLYGEVTHYA-H 138
            .:.|  ...:..|:    .:|:...|.|:     .:.|..|...:|.|:|.|:::...:.... .
Mosquito   285 QQQSIAPSVIRLGL----NEAAPVVNVEE-----TILHPEFDVASGKNNIALIKMKDAIDQSTIA 340

  Fly   139 IRPICIILDHVVKSAPFERFEGFGWQQQGTEASSQVRQTVYLSQKKP--------FECHRNGQLL 195
            |.|.|:                  |:.|.......::..:..|...|        .:|.|..: .
Mosquito   341 INPACL------------------WKNQTHTPFEMIQPVIKESTLGPALAFTKFNSDCDRTFR-R 386

  Fly   196 PINEGQFCAGNRDRSFC-RSNSGSPLTADFTYGVKNITVQVGLVSYGSELC--SPTSVYTDVVAF 257
            .::|.:.|.......:. ..:||..|.....:..|.....|.:.|:|| .|  |...|||.|..:
Mosquito   387 TLDEHELCVDVEQLPYMDTGDSGGRLQVKLLHNAKVTPFVVAVTSFGS-ACGQSTPGVYTKVSKY 450

  Fly   258 KDWIYNTV 265
            ..||.:.:
Mosquito   451 APWIRSVI 458

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33465	NP_001033950.2	Tryp_SPc	46..264	CDD:238113	50/237 (21%)
		Tryp_SPc	46..261	CDD:214473	48/234 (21%)
		Tryp_SPc	293..484	CDD:304450
		Tryp_SPc	293..481	CDD:214473
AgaP_AGAP009252	XP_320033.4	Tryp_SPc	248..457	CDD:304450	50/237 (21%)
AgaP_AGAP009252	XP_320033.4	Tryp_SPc	248..454	CDD:214473	48/234 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	156	1.000	Inparanoid score	I6716
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.960