DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33465 and CG43336

DIOPT Version :9

Sequence 1:	NP_001033950.2	Gene:	CG33465 / 3885587	FlyBaseID:	FBgn0053465	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	NP_001247122.1	Gene:	CG43336 / 12798414	FlyBaseID:	FBgn0263041	Length:	279	Species:	Drosophila melanogaster

Alignment Length:	291	Identity:	90/291 - (30%)
Similarity:	137/291 - (47%)	Gaps:	41/291 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 LSLALIGLVL----CQGLAQLLDKKC----HDPKTSENINFNHGATETAPWMASIYK-NNQFICD 60
            :::.::||..    ..|..|.||..|    |.|......|....:..::||||.::. :.:|||.
  Fly     1 MNVVVVGLTFFLLPLLGSTQFLDMACGIRAHSPSVPRVKNGTVASLTSSPWMAFLHSTDGRFICG 65

  Fly    61 GTLVHKLFVLTAASCISKDSQLYVLFGMYNQYRDASQFFNNEQYG--------------VAVALQ 111
            |:|:....|||||.|....::|....|.|::          |:|.              |....:
  Fly    66 GSLITNRLVLTAAHCFLDRTELVARLGEYDR----------EEYEMCHDSYCTYRIEAMVERGFR 120

  Fly   112 HSNFRPNNGVNDIGLLRLYGEVTHYAHIRPICIILD----HVVKSAPFERFEGFGWQQQGTEASS 172
            |.::.|.....||.:||||.:|.:..:||||||::|    ..:.|  .:...|.||.:..:|..|
  Fly   121 HRHYNPMTMAYDIAILRLYRKVQYTDNIRPICIVIDPRWRKYIDS--LDPLTGTGWGKTESEGDS 183

  Fly   173 QVRQTVYLSQKKPFECHRNGQLLPINEGQFCAGNRDRSFCRSNSGSPLTADFTYGVKNITVQVGL 237
            ...:||.|::|.|..|.|.. .|.:...||||||...:.|..:||.|:.|...||.....||||:
  Fly   184 AKLRTVDLARKHPEVCRRYA-TLSLTANQFCAGNERSNLCNGDSGGPVGALIPYGKSKRFVQVGI 247

  Fly   238 VSYGSELCSPTSVYTDVVAFKDWIYNTVRNF 268
            .|:.:..|...||:|||:::.|||. .|.|:
  Fly   248 ASFTNTQCVMVSVFTDVMSYVDWIL-AVHNY 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33465	NP_001033950.2	Tryp_SPc	46..264	CDD:238113	78/236 (33%)
		Tryp_SPc	46..261	CDD:214473	76/233 (33%)
		Tryp_SPc	293..484	CDD:304450
		Tryp_SPc	293..481	CDD:214473
CG43336	NP_001247122.1	Tryp_SPc	37..271	CDD:214473	77/246 (31%)
CG43336	NP_001247122.1	Tryp_SPc	40..271	CDD:238113	77/243 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463460
Domainoid	1	1.000	102	1.000	Domainoid score	I4289
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	108	1.000	Inparanoid score	I3480
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000404
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_108863
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.890