DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33465 and CG43335

DIOPT Version :9

Sequence 1:	NP_001033950.2	Gene:	CG33465 / 3885587	FlyBaseID:	FBgn0053465	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	NP_001247121.1	Gene:	CG43335 / 12798413	FlyBaseID:	FBgn0263040	Length:	281	Species:	Drosophila melanogaster

Alignment Length:	282	Identity:	91/282 - (32%)
Similarity:	131/282 - (46%)	Gaps:	31/282 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LIGLVLCQ-----GLAQLLDKKC--------HDPKTSENINFNHGATETAPWMASIYKNNQFICD 60
            |:.:.:||     |.::||:..|        |..:.   |..:.....:.||||.:|....:.|.
  Fly     7 LVIISVCQWLCRFGESRLLEPNCGIRTMPSFHRTRI---IGGSDAEITSHPWMAYLYNEFHYFCA 68

  Fly    61 GTLVHKLFVLTAASCISKDSQLYVLFGMYNQYR-DASQF-FNNEQYGVAVALQHSNFRPNNGVND 123
            |||:...||||||.||.....|.|..|.....| |.|.. ...|.|.|::|::|..|.|:..:||
  Fly    69 GTLITNQFVLTAAHCIEASKNLTVRLGGSGLTRSDGSMCQITAEDYSVSMAIKHKYFTPSIMLND 133

  Fly   124 IGLLRLYGEVTHYAHIRPICIILDHVVKSAPFE--RFEGFGWQQQGTEASSQVRQTVYLSQKKPF 186
            |.::||...|..|.||||||||||..|:....:  .....||      ..:..|...:|.|:.|.
  Fly   134 IAMIRLARTVKFYDHIRPICIILDPAVRLLLEDGMTLMATGW------GLADKRMHPHLLQEAPI 192

  Fly   187 E-CHRN--GQL--LPINEGQFCAGNRDRSFCRSNSGSPLTADFTYGVKNITVQVGLVSYGSELCS 246
            . .:||  .:|  :.|.:||.|||:::.:.|..:||.||.....|......||.|:.|:|...|.
  Fly   193 TVMNRNVCSKLYDVAITQGQICAGDKETNTCLGDSGGPLGGVVNYYGDLRFVQYGITSFGDIECR 257

  Fly   247 PTSVYTDVVAFKDWIYNTVRNF 268
            ..|:|||:..:..||...|..:
  Fly   258 SPSIYTDLSTYSGWINMVVSQY 279

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33465	NP_001033950.2	Tryp_SPc	46..264	CDD:238113	81/226 (36%)
		Tryp_SPc	46..261	CDD:214473	79/223 (35%)
		Tryp_SPc	293..484	CDD:304450
		Tryp_SPc	293..481	CDD:214473
CG43335	NP_001247121.1	Tryp_SPc	41..272	CDD:214473	80/239 (33%)
CG43335	NP_001247121.1	Tryp_SPc	42..275	CDD:238113	82/241 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463453
Domainoid	1	1.000	102	1.000	Domainoid score	I4289
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	108	1.000	Inparanoid score	I3480
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000404
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_108863
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.890