DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33465 and CG43124

DIOPT Version :9

Sequence 1:	NP_001033950.2	Gene:	CG33465 / 3885587	FlyBaseID:	FBgn0053465	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	NP_001247345.1	Gene:	CG43124 / 12798282	FlyBaseID:	FBgn0262587	Length:	245	Species:	Drosophila melanogaster

Alignment Length:	262	Identity:	77/262 - (29%)
Similarity:	114/262 - (43%)	Gaps:	53/262 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 LVLC------QGLAQLLDKKCHDPKTSENINFNHGATETAPWMASIYKNNQFICDGTLVHKLFVL 70
            :|||      ||.||.|::.|.|  ..|.||    .:..|||:|.|..:::.||.|.|::.|:||
  Fly     7 IVLCIVLMFYQGSAQTLEEDCVD--HMERIN----GSSYAPWLAEILSDSKVICAGALINNLYVL 65

  Fly    71 TAASCISKDSQLYVLFGMYNQYRDASQFFNNEQYGVAVALQHSNFRPNNGVNDIGLLRLYGEVTH 135
            |||||..::.:|.|..|  :.|.|.|.    |.:.|..|.......|.|..|::.:.||..||..
  Fly    66 TAASCFKENEKLTVRLG--SGYFDKSY----ENFRVTKAYFWMTHFPANNTNNLCIFRLQTEVEF 124

  Fly   136 YAHIRPICIILDHVVKSAPFERFEGFGWQQQGTEASSQVRQTVYLSQKKP---FECHRNGQLLPI 197
            ..||||:||     .||                ..|..:..|..:..:||   :.|..
  Fly   125 KTHIRPMCI-----TKS----------------PKSLGLATTFEIINEKPKMWYFCKN------- 161

  Fly   198 NEGQFCA---GNRDRSFCRSNSGSPLTADFTYGVKNITVQVGLVSYGSELCSPTSVYTDVVAFKD 259
            .:|.||.   |..:..:....:|||.|...:.|.....|:.|::||.... :...||.:|::..:
  Fly   162 IKGLFCKYVFGENEEKWQSKPTGSPWTETISNGPFKGLVRYGILSYRDNK-TYDEVYINVMSHIN 225

  Fly   260 WI 261
            ||
  Fly   226 WI 227

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33465	NP_001033950.2	Tryp_SPc	46..264	CDD:238113	63/222 (28%)
		Tryp_SPc	46..261	CDD:214473	61/220 (28%)
		Tryp_SPc	293..484	CDD:304450
		Tryp_SPc	293..481	CDD:214473
CG43124	NP_001247345.1	Tryp_SPc	41..>133	CDD:304450	36/97 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000404
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.010