DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33465 and AgaP_AGAP008277

DIOPT Version :9

Sequence 1:	NP_001033950.2	Gene:	CG33465 / 3885587	FlyBaseID:	FBgn0053465	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	XP_317194.3	Gene:	AgaP_AGAP008277 / 1277708	VectorBaseID:	AGAP008277	Length:	259	Species:	Anopheles gambiae

Alignment Length:	282	Identity:	66/282 - (23%)
Similarity:	107/282 - (37%)	Gaps:	52/282 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LALIGLVLCQGLAQLLDKKCHDPKTSENI--NFNHGATETAPWMASIYKNNQFICDGTLVHKLFV 69
            ||:|.|.:...|      |..|..|:..:  .|..| .||.|:..:|:...:.:|.|:::...:|
Mosquito     9 LAVISLPIGNFL------KPDDNNTANMVVGGFQVG-IETVPYQVAIFYAGELLCGGSIIGLHWV 66

  Fly    70 LTAASCISK--DSQLYVLFGMYNQYRDASQFFNNEQYGVAVALQHSNFRPNNGVNDIGLLRLYGE 132
            ||:..|:|.  .|...::.|:.|...|..:....:....||......:       ||.|:||...
Mosquito    67 LTSYHCVSTRIPSDYGIVVGVTNPEADGRRIHVEDFIFPAVTESDKTY-------DIALVRLNQS 124

  Fly   133 VTHYAHIR--PICIILDHVVKSAPFERFEGFGWQQQGTEASSQVRQTVYLSQKKPFECHRNGQLL 195
            :.:...::  |:..:.|.:....| ....|||:.|.|   .|:.:..:...|..|::..:.....
Mosquito   125 LVYSEAVQCIPLLSVHDAIGPGKP-AYISGFGFTQDG---GSETQLKIATIQVLPWQTCQEAYPT 185

  Fly   196 PINEGQFCAGNRDRSF-------------CRSNSGSPLTADFTYGVKNITVQVGLVSYGSELCSP 247
            .:.:...|||     |             |:.:||.||..|        ....|:|.||.....|
Mosquito   186 LMRKYLLCAG-----FMLCAGILAGGVDSCQGDSGGPLVLD--------NQLAGVVFYGIGCGEP 237

  Fly   248 T--SVYTDVVAFKDWIYNTVRN 267
            .  ..|..|..|.|||...|.|
Mosquito   238 NHPGAYISVPWFYDWIVGIVSN 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33465	NP_001033950.2	Tryp_SPc	46..264	CDD:238113	52/236 (22%)
		Tryp_SPc	46..261	CDD:214473	50/233 (21%)
		Tryp_SPc	293..484	CDD:304450
		Tryp_SPc	293..481	CDD:214473
AgaP_AGAP008277	XP_317194.3	Tryp_SPc	31..253	CDD:214473	54/246 (22%)
AgaP_AGAP008277	XP_317194.3	Tryp_SPc	31..253	CDD:238113	54/246 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24260
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010