DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33465 and AgaP_AGAP006672

DIOPT Version :9

Sequence 1:	NP_001033950.2	Gene:	CG33465 / 3885587	FlyBaseID:	FBgn0053465	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	XP_316708.4	Gene:	AgaP_AGAP006672 / 1277262	VectorBaseID:	AGAP006672	Length:	327	Species:	Anopheles gambiae

Alignment Length:	346	Identity:	89/346 - (25%)
Similarity:	135/346 - (39%)	Gaps:	110/346 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SRVLSLALIGLVLC--QGLAQLLDKKCHDPKTS------ENINFNHG-----------ATETAPW 47
            |.|..|.|:.:|||  .|.|....::...||..      :|::   |           |..||.:
Mosquito     5 SIVRCLLLLCVVLCATDGEASPTYRRSKPPKMGMFWTVIQNVS---GPPVPPSASILSAASTALY 66

  Fly    48 M---------------ASIYKNNQF----------------ICDGTLVHKLFVLTAASCISKDSQ 81
            .               .::.||:||                :|.|:::...|:||||.|
Mosquito    67 RPKLIIDRASLSKVAGGTVAKNDQFPHLVSIILIFADGSDTLCGGSILADRFILTAAHC------ 125

  Fly    82 LYVLFGMYNQYRDASQF-----FNNEQYGVAV----ALQHSNFRPNNGVNDIGLLRLYGEVTHYA 137
               |:||........|.     |..:...||:    .:.|..:.|.:.:|||.|:||...:|..|
Mosquito   126 ---LYGMQEATIVPGQSVIQIPFPPDIVTVAIKPADTILHPGYDPVDILNDIALIRLPQPLTFSA 187

  Fly   138 HIRPICII-----------LDHVVKSAPFERFEGFGWQQQGTEASSQVRQTVYLSQKKPFE---- 187
            .::||.:.           .|.:|.          ||..|..:..:::...:.|..:....
Mosquito   188 RVQPIRLPSWTNSYVDLTGYDSIVS----------GWGAQSNDDYAELVDEMRLDLRFATNTIVP 242

  Fly   188 ---CHR-NGQLLPINEGQFC-AGNRDRSFCRSNSGSPLTADFTYGVKNITVQVGLVSYGSEL-C- 245
               ||| .|.:  |.:.|.| ||...|:.|:.:||.|||..|. |.:  ..|||:|||||.| |
Mosquito   243 NAVCHRVYGSI--IRDQQICVAGEGGRNPCQGDSGGPLTVKFD-GQR--LTQVGIVSYGSVLGCE 302

  Fly   246 -SPTSVYTDVVAFKDWI-YNT 264
             ....|||.|.::.:|| |:|
Mosquito   303 NGVPGVYTRVSSYVEWIVYHT 323

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33465	NP_001033950.2	Tryp_SPc	46..264	CDD:238113	72/281 (26%)
		Tryp_SPc	46..261	CDD:214473	69/277 (25%)
		Tryp_SPc	293..484	CDD:304450
		Tryp_SPc	293..481	CDD:214473
AgaP_AGAP006672	XP_316708.4	Tryp_SPc	79..319	CDD:214473	69/263 (26%)
AgaP_AGAP006672	XP_316708.4	Tryp_SPc	80..319	CDD:238113	69/262 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910