DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33465 and AgaP_AGAP006486

DIOPT Version :9

Sequence 1:	NP_001033950.2	Gene:	CG33465 / 3885587	FlyBaseID:	FBgn0053465	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	XP_316523.4	Gene:	AgaP_AGAP006486 / 1277090	VectorBaseID:	AGAP006486	Length:	287	Species:	Anopheles gambiae

Alignment Length:	228	Identity:	61/228 - (26%)
Similarity:	87/228 - (38%)	Gaps:	45/228 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 NNQFICDGTLVHKLFVLTAASCISKD-------SQLYVLFGMYNQYRDASQFFNNEQYGVAVALQ 111
            ||.| |.|.::::..|||||.|:...       :||.:|.||....      |...:.|:.....
Mosquito    65 NNAF-CGGVILNENHVLTAARCVLTPQNTLLFANQLNILSGMLQLN------FGAPRIGITAVYV 122

  Fly   112 HSNFRPNNGVNDIGLLRLYGEVTHYAHIRPICIILDHVVKSAPFER---FEG-----FGWQQQGT 168
            |..:.|....::|.:||     |......|:..:.:  |..|.|..   |:|     .|| ..||
Mosquito   123 HPQYNPFTFEHNIAVLR-----TSSNFFFPVVPVPN--VDFAQFYEEIAFDGQPCQVVGW-NNGT 179

  Fly   169 EASSQVRQTVYLSQKKPFECHRNG---QLLPINEGQFCAG--NRDRSFCRSNSGSPLTADFTYGV 228
              ::.|:|.:.........|  ||   .|..|.|...|||  |.....|.||.|:.|   |..|.
Mosquito   180 --ATPVQQFINAPILNRDTC--NGLAVHLGNIRESMVCAGVTNAGPGVCASNLGTGL---FCEGR 237

  Fly   229 KNITVQVGLVSYGSELCSPTSVYTDVVAFKDWI 261
            ....:..||   |....:...|||.:..:..||
Mosquito   238 LAGILSTGL---GCGQANNPGVYTQIRYYLPWI 267

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33465	NP_001033950.2	Tryp_SPc	46..264	CDD:238113	61/228 (27%)
		Tryp_SPc	46..261	CDD:214473	59/226 (26%)
		Tryp_SPc	293..484	CDD:304450
		Tryp_SPc	293..481	CDD:214473
AgaP_AGAP006486	XP_316523.4	Tryp_SPc	41..270	CDD:238113	61/228 (27%)
AgaP_AGAP006486	XP_316523.4	Tryp_SPc	41..267	CDD:214473	59/226 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910