DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33465 and AgaP_AGAP005670

DIOPT Version :9

Sequence 1:	NP_001033950.2	Gene:	CG33465 / 3885587	FlyBaseID:	FBgn0053465	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	XP_315687.1	Gene:	AgaP_AGAP005670 / 1276350	VectorBaseID:	AGAP005670	Length:	300	Species:	Anopheles gambiae

Alignment Length:	218	Identity:	55/218 - (25%)
Similarity:	89/218 - (40%)	Gaps:	23/218 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 ICDGTLVHKLFVLTAASCISKDSQLY-----VLFGMYNQ-YRDASQFFNNEQYGVAVALQHSNFR 116
            :|.|:::...::||||.|:...:...     .:.|.:|: ..:.||  ...::.....::|..:.
Mosquito    82 LCGGSVLTNNYILTAAHCVVSGATTLARGGTAIMGAHNRNVNEPSQ--QRIRFSTGGIIRHPQYT 144

  Fly   117 PNNGVNDIGLLRLYGEVTHYAHIRPICIILDHVVKSAPFERF----EGFGWQQQGTEASSQVRQT 177
            ..|..|||.::||...:.....::|  ..|.....:..|..|    .|||....|:.|:|.|.:.
Mosquito   145 TTNIRNDIAVVRLDAPIVFNTRVQP--ARLPARSDTRQFGGFTGTVSGFGRVSDGSTATSAVVRF 207

  Fly   178 VYLSQKKPFECHRNGQLLPINEGQFC-AGNRDRSFCRSNSGSPLTADFTYGVKNITVQVGLVSYG 241
            .........:|........|.....| :|...||.|..:||.||...     ...::|:|:||:|
Mosquito   208 TSNPVMTNADCIARWNTALIQPQNVCLSGEGGRSACNGDSGGPLAVQ-----DGGSLQIGIVSFG 267

  Fly   242 SE-LCS--PTSVYTDVVAFKDWI 261
            |. .||  ..|||..|..|..||
Mosquito   268 SAGGCSIGMPSVYARVSFFLSWI 290

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33465	NP_001033950.2	Tryp_SPc	46..264	CDD:238113	55/218 (25%)
		Tryp_SPc	46..261	CDD:214473	53/216 (25%)
		Tryp_SPc	293..484	CDD:304450
		Tryp_SPc	293..481	CDD:214473
AgaP_AGAP005670	XP_315687.1	Tryp_SPc	54..290	CDD:214473	53/216 (25%)
AgaP_AGAP005670	XP_315687.1	Tryp_SPc	55..293	CDD:238113	55/218 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910