DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33465 and AgaP_AGAP005591

DIOPT Version :9

Sequence 1:	NP_001033950.2	Gene:	CG33465 / 3885587	FlyBaseID:	FBgn0053465	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	XP_315601.4	Gene:	AgaP_AGAP005591 / 1276277	VectorBaseID:	AGAP005591	Length:	273	Species:	Anopheles gambiae

Alignment Length:	239	Identity:	54/239 - (22%)
Similarity:	93/239 - (38%)	Gaps:	49/239 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 PWMASI-YKNNQ----FICDGTLVHKLFVLTAASCISKDSQLY---VLFGMYNQYRDASQFFNNE 102
            |:.|:: :|...    :.|.|:|:..:::||.|:|::.:|..|   :|..::|...:..|..|..
Mosquito    51 PYHAALRFKTKSSTKVYTCAGSLITPVYILTTAACVNHNSVEYAFAILGSLFNGNTEWEQHINIT 115

  Fly   103 QYGVAVALQHSNFRPNNGVNDIGLLRLYGEVTHYAHIRPICIILDHVVKSAPFERFEGFGWQQQG 167
            ..|:.:....|.:    |.|||..:.:....|...:::|  |.|..:..:..:|..||.......
Mosquito   116 MNGIRIHPPSSMY----GHNDIATIHMDHPATLNEYVQP--IRLPRLSDTRTYEMMEGTATSALN 174

  Fly   168 TEASSQVRQTVYLSQKKPFECHRNGQ-LLPINEGQFCAGNR-DRSFCRSNSGSPLTAD-----FT 225
            .:....:|..|..:.    :||...| |..|:....|.... ..|.|...:||.||.:     ..
Mosquito   175 GDGLRYLRNQVMSNA----DCHEAIQPLYNISSQHICTDTYIGGSLCGRTTGSALTVEDENGRML 235

  Fly   226 YGVKNITVQVGL--------VSYGSELCSPTSVYTDVVAFKDWI 261
            .||.|:.|...|        |||                |::||
Mosquito   236 VGVGNLIVLCDLHYPIRHIRVSY----------------FREWI 263

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33465	NP_001033950.2	Tryp_SPc	46..264	CDD:238113	54/239 (23%)
		Tryp_SPc	46..261	CDD:214473	52/237 (22%)
		Tryp_SPc	293..484	CDD:304450
		Tryp_SPc	293..481	CDD:214473
AgaP_AGAP005591	XP_315601.4	Tryp_SPc	42..264	CDD:238113	54/239 (23%)
AgaP_AGAP005591	XP_315601.4	Tryp_SPc	42..263	CDD:214473	52/237 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910