DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33465 and AgaP_AGAP005196

DIOPT Version :9

Sequence 1:	NP_001033950.2	Gene:	CG33465 / 3885587	FlyBaseID:	FBgn0053465	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	XP_314095.2	Gene:	AgaP_AGAP005196 / 1274902	VectorBaseID:	AGAP005196	Length:	264	Species:	Anopheles gambiae

Alignment Length:	242	Identity:	58/242 - (23%)
Similarity:	103/242 - (42%)	Gaps:	36/242 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 GATET----APWMAS-IYKNNQFICDGTLVHKLFVLTAASCISK---DSQLYVLFGMYNQYRDAS 96
            |.|:.    ||::|. :|.|:...|.|:::...::||||.|::.   .:...|..|..:.|...|
Mosquito    37 GGTDVEDGKAPYLAGLVYNNSATYCGGSIIAARWILTAAHCVTNVNVTNLTVVRVGTNDNYEGGS 101

  Fly    97 QFFNNEQYGVAVALQHSNFRPNNGVNDIGLLRLYGEVTHYAHIRPICIILDHVVKSAPFERFE-G 160
                  .|.:...:.|..:......||:.||||...:....|:..|.:..:.|..:|...... |
Mosquito   102 ------MYQIDRVIPHERYSAITFRNDVALLRLKTPIKFEEHVEKIELNEELVPINATLTIVGWG 160

  Fly   161 F-GWQQQGTEASSQVR-QTVYLSQKKPFECHRNGQLLPINEGQFCAGNR-DRSFCRSNSGSPLTA 222
            | ||.::..:.:..:: |.:.|::     |.:......|.....|..:| ....|:.:||||:
Mosquito   161 FVGWNKENPKRTQVIKVQHIGLNR-----CRKMANGSAIYPEHLCTFSRAGHGPCKGDSGSPV-- 218

  Fly   223 DFTYGVKNITVQVGLVSYG-SELCS---PTSVYTDVVAFKDWIYNTV 265
              .:..|    |||:||:. :.:|:   | .|...:..|..||..|:
Mosquito   219 --VWKGK----QVGVVSWAMAGVCAIGLP-DVQASIRYFYGWITKTM 258

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33465	NP_001033950.2	Tryp_SPc	46..264	CDD:238113	54/229 (24%)
		Tryp_SPc	46..261	CDD:214473	52/226 (23%)
		Tryp_SPc	293..484	CDD:304450
		Tryp_SPc	293..481	CDD:214473
AgaP_AGAP005196	XP_314095.2	Tryp_SPc	35..257	CDD:238113	57/239 (24%)
AgaP_AGAP005196	XP_314095.2	Tryp_SPc	35..254	CDD:214473	55/236 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910