DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33465 and AgaP_AGAP002432

DIOPT Version :9

Sequence 1:	NP_001033950.2	Gene:	CG33465 / 3885587	FlyBaseID:	FBgn0053465	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	XP_312513.5	Gene:	AgaP_AGAP002432 / 1273529	VectorBaseID:	AGAP002432	Length:	318	Species:	Anopheles gambiae

Alignment Length:	323	Identity:	72/323 - (22%)
Similarity:	122/323 - (37%)	Gaps:	77/323 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSRVLSLALIGLV-LCQGLAQL---------------------------LDKKCHDPKTSEN--- 34
            |...:||.::||: |..|::.|                           |......|..::|
Mosquito     1 MKFAISLTVVGLLALLHGVSPLPTISSSSYGIDWSQVRPIEEFDHIKAHLPINLRTPIATQNAPN 65

  Fly    35 ---INFNHGATETAPWMASIYKNNQF-----ICDGTLVHKLFVLTAASCI--SKDSQLYV----- 84
               :|.........|:..::.  .||     :|..:::.:.:|||||.|:  ..|:...|
Mosquito    66 RRIVNGQEARPGQFPYQVALL--GQFNAGVGLCGASIITQRYVLTAAHCVYTGVDASAPVANGTA 128

  Fly    85 LFGMYNQY--RDASQFFNNEQYGVAVALQHSNFRPNNGVNDIGLLRLYGEVTHYAHIRPICIILD 147
            :.|.:|:.  ..:.|.......||   :.|..:...:..|||.::||...:.:...|:||
Mosquito   129 ILGAHNRMIEEPSQQRITFSSSGV---IGHPGYDLFDVRNDIAVVRLDELIVYTDRIQPI----- 185

  Fly   148 HVVKSAPFERF-------EGFGWQQQGTEASSQVRQTVYLSQKKPFECHR--NGQLLPINEGQFC 203
            .:...:....|       .|:|.......|.|.|...|........:|..  :|....|.....|
Mosquito   186 RLPSRSDTRTFAGLMGTVSGYGIYSTANPALSDVLNYVLNPVMTNADCRAGWSGLEWLIEAQNIC 250

  Fly   204 -AGNRDRSFCRSNSGSPLTADFTYGVKNITVQVGLVSYGSEL-CS---PTSVYTDVVAFKDWI 261
             :|:..|:.|.|:||.|||...:    ..::|||:||:||.: |.   || |:..|..:.:||
Mosquito   251 QSGDGGRAACNSDSGGPLTVQDS----GESLQVGVVSFGSSVGCDNGVPT-VFARVTYYLEWI 308

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33465	NP_001033950.2	Tryp_SPc	46..264	CDD:238113	60/244 (25%)
		Tryp_SPc	46..261	CDD:214473	58/242 (24%)
		Tryp_SPc	293..484	CDD:304450
		Tryp_SPc	293..481	CDD:214473
AgaP_AGAP002432	XP_312513.5	Tryp_SPc	67..308	CDD:214473	59/255 (23%)
AgaP_AGAP002432	XP_312513.5	Tryp_SPc	68..311	CDD:238113	61/256 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910