DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33465 and CLIPB4

DIOPT Version :9

Sequence 1:	NP_001033950.2	Gene:	CG33465 / 3885587	FlyBaseID:	FBgn0053465	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	XP_307755.1	Gene:	CLIPB4 / 1269159	VectorBaseID:	AGAP003250	Length:	360	Species:	Anopheles gambiae

Alignment Length:	300	Identity:	73/300 - (24%)
Similarity:	124/300 - (41%)	Gaps:	66/300 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 LVLCQGL---------------AQLLDKKCHDPKTSENINFNHGATETAPWMASI-YKNNQ---- 56
            ||.|.|:               .||.|:......|.         .:..||.|.| |:...
Mosquito    80 LVCCAGVRSKGKTSLPESPNCGVQLTDRVIGGQPTK---------IDEFPWTALIEYEKPNGRFG 135

  Fly    57 FICDGTLVHKLFVLTAASCISKDSQLY----VLFGMYNQ----------YRDASQFFNNEQYGVA 107
            |.|.|:::::.::||||.||:...:.:    |..|.::.          |.||....:.|:
Mosquito   136 FHCGGSVINERYILTAAHCITSIPRGWKVHRVRLGEWDLSSTTDQEDDFYADAPIDLDIEK---- 196

  Fly   108 VALQHS--NFRPNNGVNDIGLLRLYGEVTHYAHIRPICIILDHVVKSAPFERFEGF--GWQQQGT 168
             .:.|.  |.:..:..|||.|:|...|:.:.:.|..||:.|.:.:::........:  ||.:..|
Mosquito   197 -IIVHPGYNLQDKSHHNDIALIRFNREINYSSTISAICLPLSNSLRNRKHAGLSSYAAGWGKTET 260

  Fly   169 EASSQVRQTVYLSQKKPFEC----HRNGQLLPINEGQFCAGN-RDRSFCRSNSGSPLTADFTYGV 228
            .::||.:..|.|:.....:|    .|||  :.::..|.|||. |.:..|..:||.||...    :
Mosquito   261 ASASQKKLKVELTVVDVKDCSPAYQRNG--ISLDSTQMCAGGIRGKDTCSGDSGGPLMRQ----M 319

  Fly   229 KNITVQVGLVSYGSELCSP---TSVYTDVVAFKDWIYNTV 265
            ......:|:||:|.:.|..   ..|||:|..:.|||.:.:
Mosquito   320 SGSWYLIGVVSFGPQKCGAPGVPGVYTNVAEYVDWIKDNI 359

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33465	NP_001033950.2	Tryp_SPc	46..264	CDD:238113	65/248 (26%)
		Tryp_SPc	46..261	CDD:214473	63/245 (26%)
		Tryp_SPc	293..484	CDD:304450
		Tryp_SPc	293..481	CDD:214473
CLIPB4	XP_307755.1	CLIP	31..83	CDD:371857	2/2 (100%)
CLIPB4	XP_307755.1	Tryp_SPc	108..358	CDD:238113	66/269 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910