DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33465 and klkb1

DIOPT Version :9

Sequence 1:	NP_001033950.2	Gene:	CG33465 / 3885587	FlyBaseID:	FBgn0053465	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	XP_002934450.3	Gene:	klkb1 / 100486524	XenbaseID:	XB-GENE-985051	Length:	629	Species:	Xenopus tropicalis

Alignment Length:	273	Identity:	66/273 - (24%)
Similarity:	111/273 - (40%)	Gaps:	53/273 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 KKCHDPKTSENINFNHGATETA----PWMASI-------YKNNQFICDGTLVHKLFVLTAASCIS 77
            |.|.:|  .|:.|...|.|::.    ||..|:       ||.:  .|.|:::...:::|||.|.:
Frog   379 KGCGEP--IEHANRIVGGTDSVLGEWPWQVSMHLRLTASYKKH--ACGGSIISNQWIVTAAHCFA 439

  Fly    78 KD--SQLYVLFG---MYNQYRDASQFFNNEQYGVAVALQHSNFRPNNGVNDIGLLRLYGEVTHYA 137
            ..  .|:::::.   ..:....::.|...||     .:.|.::.......||.||:|...::...
Frog   440 MHPLPQMWIIYSGVVKLSNITQSTPFSETEQ-----IIIHPHYTGAGNGTDIALLKLKTPISFND 499

  Fly   138 HIRPICIILDHVVKSAPFER---------FEGFGW-QQQGTEASSQVRQTVYLSQKKPFECHRNG 192
            |.:.||:        .|.|.         ..|:|: ::.|:.|:  :.|...:.|....||..|.
Frog   500 HQKAICL--------PPREPTFVLPNSCWITGWGFTEESGSLAN--ILQKAEVPQISTEECQGNY 554

  Fly   193 QLLPINEGQFCAGNRDRSF--CRSNSGSPLTADFTYGVKNITVQVGLVSYGSELCSP--TSVYTD 253
            :...|::...|||.:....  |:.:||.||..    .|..|....|:.|:|.....|  ..|||.
Frog   555 EQTRIDKKILCAGYKRGKIDSCKGDSGGPLAC----VVDEIWYLTGITSWGEGCARPGKPGVYTR 615

  Fly   254 VVAFKDWIYNTVR 266
            |..|.|||....|
Frog   616 VSEFTDWIIEHTR 628

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33465	NP_001033950.2	Tryp_SPc	46..264	CDD:238113	58/243 (24%)
		Tryp_SPc	46..261	CDD:214473	56/240 (23%)
		Tryp_SPc	293..484	CDD:304450
		Tryp_SPc	293..481	CDD:214473
klkb1	XP_002934450.3	APPLE	21..103	CDD:128519
		APPLE	110..193	CDD:128519
		APPLE	200..283	CDD:128519
		APPLE	290..373	CDD:128519
		Tryp_SPc	391..626	CDD:238113	60/255 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910