DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33465 and si:dkey-78l4.6

DIOPT Version :9

Sequence 1:	NP_001033950.2	Gene:	CG33465 / 3885587	FlyBaseID:	FBgn0053465	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	XP_003201079.2	Gene:	si:dkey-78l4.6 / 100034588	ZFINID:	ZDB-GENE-060503-83	Length:	251	Species:	Danio rerio

Alignment Length:	288	Identity:	72/288 - (25%)
Similarity:	110/288 - (38%)	Gaps:	63/288 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 LSLALIGLVLCQGLAQLLDKKCHDPKTSENINFNHG---ATETAPWMASIYKNNQFICDGTLVHK 66
            :::.:|.|:|...|..       .|..:.::....|   ...:.|:|.|:....|.||.|.|:..
Zfish     1 MTIIIISLLLLVSLVP-------HPTFTAHVGIVDGQEAKPHSRPYMVSVQLFGQNICGGFLISD 58

  Fly    67 LFVLTAASCISKDSQLYVLFGMYNQYRDASQFFNNEQYGVAVALQHSNFRPNNGVNDIGLLRLYG 131
            .||||||.|..::..|.|:.|.:    |..:..|::.:.|...:.|.||......|||.||:|.|
Zfish    59 QFVLTAAQCWHQNQDLTVVVGAH----DLRKRQNSKNFIVKSHITHPNFNSKTFENDIMLLKLKG 119

  Fly   132 EVTHYAHIRPICIILDHVVKSAPFERFEGF---------GWQQQGT---------EASSQVRQTV 178
            :|.....||||         |.| :..|.|         ||.:..|         ||.:.:....
Zfish   120 KVPLNNKIRPI---------SLP-KNGESFKADTPCSVAGWGRLWTKGPVSDLLLEAKTAIVNDA 174

  Fly   179 YLSQKKPFECHRNGQLLPINEGQFCAGNRDRSFCRSNSGSPLTADFTYGVKNITVQVGLVSYGSE 243
                    ||........:.....||.....| |..:.|.||..:.|        .||:..:...
Zfish   175 --------ECKLRWGSHYVPSMMICAFGHGGS-CNGDGGGPLVCNNT--------AVGVTIFRDR 222

  Fly   244 -LCSP---TSVYTDVVAFKDWIYNTVRN 267
             ||:.   .:|||.:.|:..||.:.:.|
Zfish   223 YLCNSRLLPNVYTKISAYLPWIRSIIGN 250

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33465	NP_001033950.2	Tryp_SPc	46..264	CDD:238113	65/239 (27%)
		Tryp_SPc	46..261	CDD:214473	63/236 (27%)
		Tryp_SPc	293..484	CDD:304450
		Tryp_SPc	293..481	CDD:214473
si:dkey-78l4.6	XP_003201079.2	Tryp_SPc	26..247	CDD:238113	66/251 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910