DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34041 and P4htm

DIOPT Version :9

Sequence 1:	NP_001034077.5	Gene:	CG34041 / 3885583	FlyBaseID:	FBgn0054041	Length:	568	Species:	Drosophila melanogaster
Sequence 2:	NP_083220.3	Gene:	P4htm / 74443	MGIID:	1921693	Length:	503	Species:	Mus musculus

Alignment Length:	156	Identity:	35/156 - (22%)
Similarity:	59/156 - (37%)	Gaps:	58/156 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 LGFSPLLAVLILPKWASSTKMKAYLDLDTRLKTQLRGY-------SEDLQDHISTLNRYIDDRKS 70
            |...|||  ..:|.:.|..:.:..:.|     .|::|.       :|:.::.:|.:      :.|
Mouse   139 LSLKPLL--FEIPGFLSDEECRLIIHL-----AQMKGLQRSQILPTEEYEEAMSAM------QVS 190

  Fly    71 ELDKVGKDPEVYLGNPLNSFSLLHHLHFDWPAWRKLMEKPLAT------EYIT--EIQEMWSEM- 126
            :||               .|.||...|    ..|..:.:.||.      .::|  .||||:|.:
Mouse   191 QLD---------------LFQLLDQNH----DGRLQLREVLAQTRLGNGRWMTPENIQEMYSAIK 236

  Fly   127 --PTKD------EYTNSIKAAKDFHK 144
              |..|      |::|  ...:||||
Mouse   237 ADPDGDGVLSLQEFSN--MDLRDFHK 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34041	NP_001034077.5	P4Ha_N	29..138	CDD:285528	26/132 (20%)
		P4Ha_N	260..389	CDD:285528
		TPR repeat	452..491	CDD:276809
P4htm	NP_083220.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..49
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	90..110
		EF-hand_7	193..253	CDD:290234	18/80 (23%)
		EFh	195..253	CDD:298682	17/63 (27%)
		P4Hc	247..459	CDD:214780	6/16 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839360
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.840