DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34041 and P4ha1

DIOPT Version :9

Sequence 1:	NP_001034077.5	Gene:	CG34041 / 3885583	FlyBaseID:	FBgn0054041	Length:	568	Species:	Drosophila melanogaster
Sequence 2:	NP_742059.2	Gene:	P4ha1 / 64475	RGDID:	621000	Length:	534	Species:	Rattus norvegicus

Alignment Length:	368	Identity:	70/368 - (19%)
Similarity:	140/368 - (38%)	Gaps:	67/368 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   238 ILSVGLIIVYLSYSNSENRHSLSKSKVINILKIQENVVKYLENYIYALETKLKTID------EAL 296
            :|.:|::   |...::......|..::.:::..::::|..|::||.|.|.||:.|.      :.|
  Rat     5 VLMMGIL---LPQCSAHPGFFTSIGQMTDLIHNEKDLVTSLKDYIKAEEDKLEQIKKWAEKLDRL 66

  Fly   297 IDLATYHIQFERDKLAIASSPVASYSLIHHMQSDWTHWQLFLQEDPGKDELASLMSIKKYLPTKN 361
            ...||      :|.......||.::.|:..:.::|:..:..:.:|.....:::|...::|.|...
  Rat    67 TSTAT------KDPEGFVGHPVNAFKLMKRLNTEWSELENLILKDMSDGFISNLTIQRQYFPNDE 125

  Fly   362 DISEVCHGISKMLNAYLMTAQDIANGVILGTQTKYISSALKLEYLYMEIICNRHLMSLRDCVALS 426
            |.......:.::.:.|.:....|:.|.:.|.:                   ::..::..||..|.
  Rat   126 DQVGAAKALFRLQDTYNLDTNTISKGNLPGVK-------------------HKSFLTAEDCFELG 171

  Fly   427 DHSMEMKDYNKSKEWLNVAISMLESSAYWDPIVPSADLYLKLAEVYVKQQNWTLALETVEFALKS 491
            ..:....||..::.|:..|:..||..........|...||..| || :|.:...||...:..|:.
  Rat   172 KVAYTEADYYHTELWMEQALMQLEEGEMSTVDKVSVLDYLSYA-VY-QQGDLDKALLLTKKLLEL 234

  Fly   492 NPR----NAQLIRMQKRLSYHILLG------------PPKSPKLNI----ENNDYRL-------- 528
            :|.    |..|:..:..:|......            .||...:.:    |...|.:
  Rat   235 DPEHQRANGNLVYFEYIMSKEKDANKSASGDQSDQKTTPKKKGIAVDYLPERQKYEMLCRGEGIK 299

  Fly   529 ---RKNGSLYCFYDTKIRTFYSLLAPIKAEVLFIDPLVILYHE 568
               |:...|:|.|....|....:|||.|.|..:..|.:|.:|:
  Rat   300 MTPRRQKRLFCRYHDGNRNPKFILAPAKQEDEWDKPRIIRFHD 342

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34041	NP_001034077.5	P4Ha_N	29..138	CDD:285528
		P4Ha_N	260..389	CDD:285528	26/134 (19%)
		TPR repeat	452..491	CDD:276809	10/38 (26%)
P4ha1	NP_742059.2	P4Ha_N	25..112	CDD:400573	18/92 (20%)
		TPR	205..238		11/34 (32%)
		P4Hc	345..518	CDD:214780
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810