DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34041 and zgc:152670

DIOPT Version :9

Sequence 1:	NP_001034077.5	Gene:	CG34041 / 3885583	FlyBaseID:	FBgn0054041	Length:	568	Species:	Drosophila melanogaster
Sequence 2:	NP_001070123.2	Gene:	zgc:152670 / 557059	ZFINID:	ZDB-GENE-060929-954	Length:	490	Species:	Danio rerio

Alignment Length:	349	Identity:	77/349 - (22%)
Similarity:	124/349 - (35%)	Gaps:	81/349 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   251 SNSENRHSLSKSKVINILKIQENVVKYLENYIYALETKLKTIDEALIDLATYHIQFERDKLAIAS 315
            |.:|.....|..:|..:...:||::.....||.|.|..||.:...|:.|........:.......
Zfish    17 SITEQEFFSSVDQVSQLFNEEENLLDTFSLYIDAEEENLKKMKSLLLLLQLGSFSNPQSPEETMR 81

  Fly   316 SPVASYSLIHHMQSDWTHWQLFLQEDPGKDELASLMSIKKYLPTKNDISEVCHGISKMLNAYLMT 380
            .|||::.|:..::.:|.:...|.|:.. ..|..:|:.. ..:|...||:....|:..:...|.:.
Zfish    82 DPVAAFKLLKRLRHEWVNIAKFTQQSL-YQEFQTLLDY-SLIPELEDINSAALGLIGLQEIYKLY 144

  Fly   381 AQDIANGVILGTQTKYISSALKLE-------YLYMEIICNRHLMSLRDCVALSDHSMEMKDYNKS 438
            ..:|.....|.....|....:..|       :|:.....||          |:|.|...|
Zfish   145 PHNITKETPLSADEAYYIGLVAYEEDKFQHAFLWFLHSLNR----------LTDFSSTTK----- 194

  Fly   439 KEWLNVAISMLESSAYWDPIVPSADLYLKLAEVYVKQQNWTLALETVEFALKSNPRNAQ------ 497
                |..:..|.||||....:|.|        :|..|:           .|..:|.|.:
Zfish   195 ----NDLLRFLSSSAYQFGSLPVA--------IYFGQK-----------LLNLDPSNEEIKVQLG 236

  Fly   498 ---LIRMQKRLSYHILLGPPKSPKLNIE-NNDYRL-----------RKNGSLYCFYDT---KIRT 544
               |||:|:..:       |....||.: ||.|..           ::..:|.|.|.|   ..|.
Zfish   237 LYRLIRLQRTSN-------PDIFTLNTQSNNSYEALCRGEVDERTSKRQRALSCRYSTGGGNPRL 294

  Fly   545 FYSLLAPIKAEVLFIDPLVILYHE 568
            .|   ||:|.|.|:.:|.:|.||:
Zfish   295 MY---APVKEEELWDEPKIIRYHD 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34041	NP_001034077.5	P4Ha_N	29..138	CDD:285528
		P4Ha_N	260..389	CDD:285528	27/128 (21%)
		TPR repeat	452..491	CDD:276809	8/38 (21%)
zgc:152670	NP_001070123.2	P4Ha_N	26..150	CDD:285528	27/125 (22%)
zgc:152670	NP_001070123.2	P4Hc	318..474	CDD:214780
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810