Protein Alignment CG34041 and P4HTM

DIOPT Version :10

• Sequence 1: NP_001034077.5
• Gene: CG34041 / 3885583
• FlyBaseID: FBgn0054041
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_808807.2
• Gene: P4HTM / 54681
• HGNCID: 28858
• Length: 563
• Species: Homo sapiens
• Alignment Length: 180
• Identity: 35/180 - (19%)
• Similarity: 68/180 - (37%)
• Gaps: 49/180 - (27%)

  Fly   388 VILGTQTKYISSALKLEYLYMEIICNRHLMSLRDCVALSDHSMEMKDYNKSK----EWLNVAISM 448
            |.|.|...:....|.|:.|..||   ...::..:| .|..|..:||...:|:    |....|:|.
Human   125 VQLVTDRDHFIRTLSLKPLLFEI---PGFLTDEEC-RLIIHLAQMKGLQRSQILPTEEYEEAMST 185

  Fly   449 LESSA--YWDPIVPSADLYLKLAEVYVKQQ---NWTLALETVE---FALKSNPRNAQLIRMQKRL 505
            ::.|.  .:..:..:.|.:|:|.||..:.:   .|.:..|:::   .|:|::|....::.:|:
Human   186 MQVSQLDLFRLLDQNRDGHLQLREVLAQTRLGNGWWMTPESIQEMYAAIKADPDGDGVLSLQE-- 248

  Fly   506 SYHILLGPPKSPKLNIENNDYRLRKNGSLYCFYDTKIRTFYSLLAPIKAE 555
                                           |.:..:|.|:..:...|||
Human   249 -------------------------------FSNMDLRDFHKYMRSHKAE 267

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34041	NP_001034077.5	P4Ha_N	29..138	CDD:462433
		P4Ha_N	260..391	CDD:462433	1/2 (50%)
		LapB	<435..>505	CDD:442196	16/81 (20%)
		TPR repeat	452..491	CDD:276809	9/46 (20%)
P4HTM	NP_808807.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..29
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	89..111
		EF-hand_7	192..252	CDD:463900	12/92 (13%)
		P4Hc	246..519	CDD:214780	7/55 (13%)