DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34041 and p4ha2

DIOPT Version :9

Sequence 1:	NP_001034077.5	Gene:	CG34041 / 3885583	FlyBaseID:	FBgn0054041	Length:	568	Species:	Drosophila melanogaster
Sequence 2:	XP_012814344.2	Gene:	p4ha2 / 493342	XenbaseID:	XB-GENE-957618	Length:	537	Species:	Xenopus tropicalis

Alignment Length:	377	Identity:	69/377 - (18%)
Similarity:	141/377 - (37%)	Gaps:	73/377 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   226 HQMEFIVMKSACILSVGLIIVYLSYSNSENRHSLSKSKVINILKIQENVVKYLENYIYALETKLK 290
            |.:..|::...||..|            :.....|..::.:::..:.::::.|:.||...|.:|.
Frog     4 HAISLILLSLCCIWEV------------QTEVFTSTGQMTDLIFRERDLLQSLKEYIREEEERLS 56

  Fly   291 TIDEALIDLATYHIQFERDKLAIASSPVASYSLIHHMQSDWTHWQLFLQEDPGKDELASLMSIKK 355
            .|.....::.....:...|.......||.:|.|:....:||:..:..:.:|..|..:|:....::
Frog    57 KIKRWASEVDELSSRSTADPEGYLGHPVNAYKLVKRFNTDWSSLENLVLQDSAKGFIANFTFQRE 121

  Fly   356 YLPTKNDISEVCHGISKMLNAYLMTAQDIANGVILGTQTKYISSALKLEYLYMEIICNRHLMSLR 420
            |.||:.|.:.....:.::.:.|.:....||.|.:.|  |.||||                 :|..
Frog   122 YFPTEEDETGAARALMRIQDTYKLDPDVIAKGKLPG--TNYISS-----------------LSAD 167

  Fly   421 DCVALSDHSMEMKDYNKSKEWLNVAISMLESSAYWDPIVPSADLYLKLAEVYVKQQNWTLALETV 485
            |...:...:....||..:..|:..|:..::...  |.:|...|:...|:....:..:...|||..
Frog   168 DSFGMGKIAYHDGDYYHTVLWMQQALKQMDEGE--DAVVNKVDVLDYLSYTVFQLGDVPRALELT 230

  Fly   486 EFALKSNPRNAQLI-------RMQKRLSYHILLGPPKSPKLNIENN-----------DY------ 526
            :..|..:|.:.:.:       :||::....:    .::...|.|:.           ||
Frog   231 KRLLALDPNHDRAVNNLKYFEKMQEKQKAEL----KQNESTNTESATRQPGVYSRPLDYLPERDV 291

  Fly   527 ------------RLRKNGSLYCFYDTKIRTFYSLLAPIKAEVLFIDPLVILY 566
                        ..|:...|:|.|....|:.|.:|:|:|.|..:..|.::.|
Frog   292 YEALCRGEGVKMNPRRQRRLFCRYHNGNRSPYLILSPVKVEDEWDSPRIVRY 343

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34041	NP_001034077.5	P4Ha_N	29..138	CDD:285528
		P4Ha_N	260..389	CDD:285528	25/128 (20%)
		TPR repeat	452..491	CDD:276809	8/38 (21%)
p4ha2	XP_012814344.2	P4Ha_N	27..113	CDD:400573	15/85 (18%)
		TPR repeat	166..201	CDD:276809	5/36 (14%)
		TPR repeat	206..236	CDD:276809	6/29 (21%)
		P4Hc	348..521	CDD:214780
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000