DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34041 and PH4alphaNE2

DIOPT Version :9

Sequence 1:	NP_001034077.5	Gene:	CG34041 / 3885583	FlyBaseID:	FBgn0054041	Length:	568	Species:	Drosophila melanogaster
Sequence 2:	NP_733378.1	Gene:	PH4alphaNE2 / 43628	FlyBaseID:	FBgn0039783	Length:	542	Species:	Drosophila melanogaster

Alignment Length:	365	Identity:	101/365 - (27%)
Similarity:	173/365 - (47%)	Gaps:	65/365 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   238 ILSVGLIIVYLSY-----SNSENRHSLSKSKVINILKIQENVVKYLENYIYALETKLKTIDEALI 297
            ::.:|::.:.||:     :|::.|.:.|...:.::|.:::::|..:|....||..|.|||...:.
  Fly     6 LVLLGMLYLSLSFGQLRENNAQQRFARSVVNMDDMLNLEDDLVSNVEKLAEALARKAKTIKWGVF 70

  Fly   298 DLATYHIQFERDKLAIASSPVASYSLIHHMQSDWTHWQLFLQEDPGKDELASLMSIKKYLPTKND 362
            .:.....:: :..:.|.::|:.::|||.||||:|..|.|:|:...|::||..:.|....||...|
  Fly    71 KMMKRRQEY-KSSMEIFANPIDTFSLIRHMQSNWLMWLLYLETPVGQEELFFVDSRMPLLPKYFD 134

  Fly   363 ISEVCHGISKMLNAYLMTAQDIANGVILGTQTKYISSALKLEYLYMEIICNRHLMSLRDCVALSD 427
            ..:...||.||...|.|.:.|||.|::.|.|  |.||...:                 ||:|:..
  Fly   135 FIDAAEGIRKMQATYQMFSSDIAKGLLDGVQ--YNSSLKPI-----------------DCLAIGL 180

  Fly   428 HSMEMKDYNKSKEWLNVAISML-ESSAYWD------PIVPSADLYLKLAEVYVKQQNWTLALETV 485
            |.|....:..:::|::.:|... :.|:..|      |.:  |||...|.:|.:||:|...||:..
  Fly   181 HLMNNSRWYAAEQWISASIEAYDQKSSQTDMELLRGPKL--ADLCRILGQVQMKQRNHEGALQAY 243

  Fly   486 EFALKSNPRNAQLIRMQKRLSYHIL---------LGPPKSPKLNIENNDYRL------------- 528
            :.|||.:|.:.::..     .|.||         :.|.:..|   :|:..||
  Fly   244 QVALKLSPHDPEIYE-----EYRILEKRDLTLSDIEPIEQDK---DNSHERLVLPPCCSGRCQVP 300

  Fly   529 RKNGSLYCFYDTKIRTFYSLLAPIKAEVLFIDPLVILYHE 568
            |...:|||.|:.....|.. |||||.|:|.|||.|:|.|:
  Fly   301 RNLSNLYCVYNHVTSPFLQ-LAPIKTEILSIDPFVVLLHD 339

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34041	NP_001034077.5	P4Ha_N	29..138	CDD:285528
		P4Ha_N	260..389	CDD:285528	40/128 (31%)
		TPR repeat	452..491	CDD:276809	15/44 (34%)
PH4alphaNE2	NP_733378.1	P4Ha_N	33..161	CDD:285528	40/128 (31%)
		TPR repeat	175..200	CDD:276809	5/24 (21%)
		TPR_16	176..254	CDD:290168	22/79 (28%)
		TPR repeat	219..249	CDD:276809	12/31 (39%)
		TPR_2	220..253	CDD:285020	14/32 (44%)
		P4Hc	342..513	CDD:214780
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461983
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.840