DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34041 and CG18234

DIOPT Version :9

Sequence 1:	NP_001034077.5	Gene:	CG34041 / 3885583	FlyBaseID:	FBgn0054041	Length:	568	Species:	Drosophila melanogaster
Sequence 2:	NP_649043.3	Gene:	CG18234 / 40024	FlyBaseID:	FBgn0265268	Length:	515	Species:	Drosophila melanogaster

Alignment Length:	365	Identity:	78/365 - (21%)
Similarity:	162/365 - (44%)	Gaps:	69/365 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   230 FIVMKSACILSVGLIIVYLSYSNSENRHSLSKSKVINILKIQENVVKYLENYIYALETKLKTIDE 294
            ||:: |.|::|:|..|.....:||    ::|.:.:..::.::...:..:|:|..||:.|:..::.
  Fly     2 FIIL-SICLISLGPPIGLCEITNS----AMSIAGMKELVDLEGFFISEMESYTAALKNKIDLMES 61

  Fly   295 ALIDLATYHIQFERDKLAIASSPVASYSLIHHMQSDWTHWQLFLQEDPGKDELASL-MSIKKYLP 358
            .|.::.:......|:.....:.|:.::|||..:..|||..:|.:....|.:.|.:: ..:::..|
  Fly    62 LLQEVQSKREISRRNPEEFVAHPLNAFSLIRRLHEDWTQAELLMLNQVGLEHLQAIETGLEEAQP 126

  Fly   359 TKNDISEVCHGISKMLNAYLMTAQDIANGVILGTQTKYISSALKLEYLYMEIICNRHLMSLRDCV 423
            :.||:::...||..:...|.:...|||||:::|.|                  .|..|.:| :|.
  Fly   127 SDNDLNDAIGGIISLQQFYNLQPSDIANGLLMGQQ------------------YNASLTTL-NCQ 172

  Fly   424 ALSDHSMEMKDYNK-SKEWLNVAISML----ESSAY---WDPIVPSADLYLKLAEVYV----KQQ 476
            ||::..|.. :|:| :..|...|:...    :...|   :|..:|  |||:....|.|    ::.
  Fly   173 ALANACMNF-NYDKYALNWFKAAVDHYNDDRDGQVYREVFDFRLP--DLYINYTSVLVTKGFRKA 234

  Fly   477 NWTLALETVEFALKSNPRNAQLIRMQKRLSYHILLGPPKSPKLNIENNDYRL------------- 528
            .|.:..:..:.       :|.|..::|.: |.:       .|:::.:..:.:
  Fly   235 AWKVLQDVADL-------DATLWLLRKDI-YEV-------GKIDVPDPTFIITPWFDVTGCLRVG 284

  Fly   529 RKNGSLYCFYDTKIRTFYSLLAPIKAEVLFIDPLVILYHE 568
            :.:..|.|.|:.....|.. :||:|.|.|.:.|.::|||:
  Fly   285 QTSQHLSCHYEKNTSEFLR-IAPLKVETLSLKPHIVLYHD 323

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34041	NP_001034077.5	P4Ha_N	29..138	CDD:285528
		P4Ha_N	260..389	CDD:285528	29/129 (22%)
		TPR repeat	452..491	CDD:276809	9/45 (20%)
CG18234	NP_649043.3	P4Ha_N	27..157	CDD:285528	29/129 (22%)
CG18234	NP_649043.3	P4Hc	<371..485	CDD:214780
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461991
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.840