DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG34041 and P4ha2

DIOPT Version :9

Sequence 1:	NP_001034077.5	Gene:	CG34041 / 3885583	FlyBaseID:	FBgn0054041	Length:	568	Species:	Drosophila melanogaster
Sequence 2:	NP_001101745.1	Gene:	P4ha2 / 360526	RGDID:	1309673	Length:	535	Species:	Rattus norvegicus

Alignment Length:	356	Identity:	69/356 - (19%)
Similarity:	131/356 - (36%)	Gaps:	63/356 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   248 LSYSNSENRHSLSKSKVINILKIQENVVKYLENYIYALETKLKTIDEALIDLATYHIQFERDKLA 312
            ||:..:|...|:  ..:.:::..::::|:.|:.||.|.|.||..|......:.....:...|...
  Rat    16 LSWVQAEFFTSI--GHMTDLIYAEKDLVQSLKEYILAEEAKLSKIKSWASKMEALTSKSAADPEG 78

  Fly   313 IASSPVASYSLIHHMQSDWTHWQLFLQEDPGKDELASLMSIKKYLPTKNDISEVCHGISKMLNAY 377
            ..:.||.:|.|:..:.:||......:.:|.....:|:|...:::.||..|.|.....:.::.:.|
  Rat    79 YLAHPVNAYKLVKRLNTDWPALGDLVLQDAAAGFVANLSVQRQFFPTDEDESGAARALMRLQDTY 143

  Fly   378 LMTAQDIANGVILGTQTKYISSALKLEYLYMEIICNRHLMSLRDCVALSDHSMEMKDYNKSKEWL 442
            .:....|:.|.:.|  |||                 :.::|:.||..:...:....||..:..|:
  Rat   144 KLDPDMISRGELPG--TKY-----------------QAMLSVDDCFGMGRSAYNEGDYYHTVLWM 189

  Fly   443 NVAISMLESSAYWDPIVPSADLYLKLAEVYVKQQNWTL-----ALETVEFALKSNPRN------- 495
            ...:..|::.       ..|.:...|...|:....:.|     |:|.....|..:|.:
  Rat   190 EQVLKQLDAG-------EEATVTKSLVLDYLSYAVFQLGDLHRAVELTRRLLSLDPSHERAGGNL 247

  Fly   496 ---AQLIRMQ--KRLSYHILLGPPKSPKLNIENNDY------------------RLRKNGSLYCF 537
               .:|:..:  |.||.....|......|.....||                  ..|:...|:|.
  Rat   248 RYFERLLEEERGKSLSNQTDAGLASQENLYERPVDYLPERDVYESLCRGEGIKMTPRRQKRLFCR 312

  Fly   538 YDTKIRTFYSLLAPIKAEVLFIDPLVILYHE 568
            |....|....|:||.|.|..:..|.::.|::
  Rat   313 YHHGNRVPQLLIAPFKEEDEWDSPHIVRYYD 343

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34041	NP_001034077.5	P4Ha_N	29..138	CDD:285528
		P4Ha_N	260..389	CDD:285528	26/128 (20%)
		TPR repeat	452..491	CDD:276809	7/43 (16%)
P4ha2	NP_001101745.1	P4Ha_N	27..104	CDD:400573	16/78 (21%)
P4ha2	NP_001101745.1	P4Hc	346..519	CDD:214780
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810