DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34041 and CG31013

DIOPT Version :9

Sequence 1:	NP_001034077.5	Gene:	CG34041 / 3885583	FlyBaseID:	FBgn0054041	Length:	568	Species:	Drosophila melanogaster
Sequence 2:	NP_733394.3	Gene:	CG31013 / 326111	FlyBaseID:	FBgn0051013	Length:	534	Species:	Drosophila melanogaster

Alignment Length:	335	Identity:	94/335 - (28%)
Similarity:	163/335 - (48%)	Gaps:	34/335 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   248 LSYSNSENRHSLSKSKVINILKIQENVVKYLENYIYALETKLKTIDEALIDLATYHIQFERDKLA 312
            |.:...|..||||...::.:|::::.::..||||..|||.||:.|...|:.:...:.:..|:.::
  Fly    19 LGHRPLEKSHSLSLVTMVPLLELEKKLIDNLENYTNALEQKLEIIRSQLLVIRAENEKGRRNAIS 83

  Fly   313 IASSPVASYSLIHHMQSDWTHWQLFLQEDPGKDELASLMSIKKYLPTKNDISEVCHGISKMLNAY 377
            ..|:|:..:|:|..:..||.:|:.::::..|..:|.:..|.|..|||:.|:.:.|.||:::.:.|
  Fly    84 YLSNPLNGFSIIRRLHQDWINWRKYMEQPVGIWQLKAFYSWKDELPTERDLWDACEGIARIQSTY 148

  Fly   378 LMTAQDIANGVILGTQTKYISSALKLEYLYMEIICNRHLMSLRDCVALSDHSMEMKDYNKSKEWL 442
            .:...|..||.|.|.|  |..|                 ||..|.:::..:.......:.:.:||
  Fly   149 DLKVGDFINGNINGKQ--YNDS-----------------MSTADILSVGAYLFMKNRPSDAIQWL 194

  Fly   443 NVAISMLESSAYWDP---IVPSADLYLKLAEVYVKQQNWTLALETVEFALKSNPRNAQLIRMQKR 504
            ......|:......|   .:...|....|||..:|.||::.||..:...||..|.:|:::|:.|:
  Fly   195 QEVPQRLQEELLIQPRHLPIKEVDALRLLAEAQIKDQNYSEALPLLHNCLKLQPHDARVLRLWKK 259

  Fly   505 LSYHILLGPPKSPKLNIEN-----NDYRLRKNG------SLYCFYDTKIRTFYSLLAPIKAEVLF 558
            .:..|...|.:||..|.:.     |.::|..||      .|:|||:.....|.. |||:|.|.:.
  Fly   260 TTDFIENQPDQSPTENKKRNVPIANAFKLSCNGPLESSTRLHCFYNFTTTPFLR-LAPLKTEQIG 323

  Fly   559 IDPLVILYHE 568
            :||.|:||||
  Fly   324 LDPYVVLYHE 333

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34041	NP_001034077.5	P4Ha_N	29..138	CDD:285528
		P4Ha_N	260..389	CDD:285528	36/128 (28%)
		TPR repeat	452..491	CDD:276809	11/41 (27%)
CG31013	NP_733394.3	P4Ha_N	31..160	CDD:285528	36/128 (28%)
		TPR_11	178..248	CDD:290150	15/69 (22%)
		TPR repeat	211..246	CDD:276809	10/34 (29%)
		P4Hc	336..513	CDD:214780
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462013
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.840