DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34041 and P4ha2

DIOPT Version :9

Sequence 1:	NP_001034077.5	Gene:	CG34041 / 3885583	FlyBaseID:	FBgn0054041	Length:	568	Species:	Drosophila melanogaster
Sequence 2:	XP_006532515.1	Gene:	P4ha2 / 18452	MGIID:	894286	Length:	557	Species:	Mus musculus

Alignment Length:	369	Identity:	71/369 - (19%)
Similarity:	137/369 - (37%)	Gaps:	65/369 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   239 LSVGLIIVYLSY----SNSENRHSLSKSKVINILKIQENVVKYLENYIYALETKLKTIDEALIDL 299
            |.|.::::.:|:    |..:.....|...:.:::..::::|:.|:.||...|.||..|......:
Mouse     3 LQVLVLVLLMSWFGVLSWVQAEFFTSIGHMTDLIYAEKDLVQSLKEYILVEEAKLAKIKSWASKM 67

  Fly   300 ATYHIQFERDKLAIASSPVASYSLIHHMQSDWTHWQLFLQEDPGKDELASLMSIKKYLPTKNDIS 364
            .....:...|.....:.||.:|.|:..:.:||......:.:|.....:|:|...:::.||..|.|
Mouse    68 EALTSRSAADPEGYLAHPVNAYKLVKRLNTDWPALGDLVLQDASAGFVANLSVQRQFFPTDEDES 132

  Fly   365 EVCHGISKMLNAYLMTAQDIANGVILGTQTKYISSALKLEYLYMEIICNRHLMSLRDCVALSDHS 429
            .....:.::.:.|.:....|:.|.:.|  |||                 :.::|:.||..|...:
Mouse   133 GAARALMRLQDTYKLDPDTISRGELPG--TKY-----------------QAMLSVDDCFGLGRSA 178

  Fly   430 MEMKDYNKSKEWLNVAISMLESSAYWDPIVPSADLYLKLAEVYVKQQNWTL-----ALETVEFAL 489
            ....||..:..|:...:..|::.       ..|.:...|...|:....:.|     |:|.....|
Mouse   179 YNEGDYYHTVLWMEQVLKQLDAG-------EEATVTKSLVLDYLSYAVFQLGDLHRAVELTRRLL 236

  Fly   490 KSNPRN----------AQLIRMQ--KRLSYHILLGPPKSPKLNIENNDY---------------- 526
            ..:|.:          .:|:..:  |.||.....|......|.....||
Mouse   237 SLDPSHERAGGNLRYFERLLEEERGKSLSNQTDAGLATQENLYERPTDYLPERDVYESLCRGEGV 301

  Fly   527 RL--RKNGSLYCFYDTKIRTFYSLLAPIKAEVLFIDPLVILYHE 568
            :|  |:...|:|.|....|....|:||.|.|..:..|.::.|::
Mouse   302 KLTPRRQKKLFCRYHHGNRVPQLLIAPFKEEDEWDSPHIVRYYD 345

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34041	NP_001034077.5	P4Ha_N	29..138	CDD:285528
		P4Ha_N	260..389	CDD:285528	26/128 (20%)
		TPR repeat	452..491	CDD:276809	7/43 (16%)
P4ha2	XP_006532515.1	P4Ha_N	28..157	CDD:369820	26/128 (20%)
P4ha2	XP_006532515.1	P4Hc	348..541	CDD:214780
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810