DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34041 and P4ha1

DIOPT Version :9

Sequence 1:	NP_001034077.5	Gene:	CG34041 / 3885583	FlyBaseID:	FBgn0054041	Length:	568	Species:	Drosophila melanogaster
Sequence 2:	NP_001303300.1	Gene:	P4ha1 / 18451	MGIID:	97463	Length:	534	Species:	Mus musculus

Alignment Length:	346	Identity:	68/346 - (19%)
Similarity:	132/346 - (38%)	Gaps:	64/346 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   260 SKSKVINILKIQENVVKYLENYIYALETKLKTID------EALIDLATYHIQFERDKLAIASSPV 318
            |..::.:::..::::|..|::||.|.|.||:.|.      :.|...||      :|.......||
Mouse    24 SIGQMTDLIHNEKDLVTSLKDYIKAEEDKLEQIKKWAEKLDRLTSTAT------KDPEGFVGHPV 82

  Fly   319 ASYSLIHHMQSDWTHWQLFLQEDPGKDELASLMSIKKYLPTKNDISEVCHGISKMLNAYLMTAQD 383
            .::.|:..:.::|:..:..:.:|.....:::|...::|.|...|.......:.::.:.|.:....
Mouse    83 NAFKLMKRLNTEWSELENLILKDMSDGFISNLTIQRQYFPNDEDQVGAAKALFRLQDTYNLDTNT 147

  Fly   384 IANGVILGTQTKYISSALKLEYLYMEIICNRHLMSLRDCVALSDHSMEMKDYNKSKEWLNVAISM 448
            |:.|.:.|.|                   ::..::..||..|...:....||..::.|:..|::.
Mouse   148 ISKGNLPGVQ-------------------HKSFLTAEDCFELGKVAYTEADYYHTELWMEQALTQ 193

  Fly   449 LESSAYWDPIVPSADLYLKLAEVYVKQQNWTLALETVEFALKSNPR----NAQLIRMQKRLSYHI 509
            ||..........|...||..| || :|.:...||...:..|:.:|.    |..|:..:..:|...
Mouse   194 LEEGELSTVDKVSVLDYLSYA-VY-QQGDLDKALLLTKKLLELDPEHQRANGNLVYFEYIMSKEK 256

  Fly   510 LLG------------PPKSPKLNI----ENNDYRL-----------RKNGSLYCFYDTKIRTFYS 547
            ...            .||...:.:    |...|.:           |:...|:|.|....|....
Mouse   257 DANKSASGDQSDQKTAPKKKGIAVDYLPERQKYEMLCRGEGIKMTPRRQKRLFCRYHDGNRNPKF 321

  Fly   548 LLAPIKAEVLFIDPLVILYHE 568
            :|||.|.|..:..|.:|.:|:
Mouse   322 ILAPAKQEDEWDKPRIIRFHD 342

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34041	NP_001034077.5	P4Ha_N	29..138	CDD:285528
		P4Ha_N	260..389	CDD:285528	26/134 (19%)
		TPR repeat	452..491	CDD:276809	10/38 (26%)
P4ha1	NP_001303300.1	P4Ha_N	24..153	CDD:285528	26/134 (19%)
		TPR	205..238		11/34 (32%)
		P4Hc	345..518	CDD:214780
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810