DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34041 and p4ha3

DIOPT Version :9

Sequence 1:	NP_001034077.5	Gene:	CG34041 / 3885583	FlyBaseID:	FBgn0054041	Length:	568	Species:	Drosophila melanogaster
Sequence 2:	XP_031752143.1	Gene:	p4ha3 / 100495824	XenbaseID:	XB-GENE-962355	Length:	547	Species:	Xenopus tropicalis

Alignment Length:	355	Identity:	83/355 - (23%)
Similarity:	145/355 - (40%)	Gaps:	78/355 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   260 SKSKVINILKIQENVVKYLENYIYALETKLKTIDEALIDLATYHIQFERDKLA---IASSPVASY 321
            |.:.:...:.::..::::|..|:.. ||      :.|.||..::.:.:....|   ....|:.:|
Frog    34 SMASIQQAVGMEGALLQHLGQYLQQ-ET------QRLSDLRRFYEKVQASHQAGGPPVQDPILAY 91

  Fly   322 SLIHHMQSDWTHWQLFLQEDPGKDELASLM----SIKKYLPTKNDISEVCHGISKMLNAYLMTAQ 382
            :|:..:||:|.:   .:......:.:.:|.    .:|:.||...|:    .|.:|.    ||..|
Frog    92 TLLKRLQSEWMN---VVHSSEANENIQALKEGYEKVKQDLPAPEDV----EGAAKA----LMRLQ 145

  Fly   383 DI----ANGVILGTQTKYISSALKLEYLYMEIICNRHLMSLRDCVALSDHSMEMKDYNKSKEWLN 443
            |:    .||:..|...:..||..||.|....:    .:||..||..:...:.:|:||..|..||.
Frog   146 DVYSLNVNGLARGMFQRSSSSDTKLLYNPPHL----SIMSADDCFHIGKVAYDMEDYYHSIPWLE 206

  Fly   444 VAISMLESS-AYW----DPIVPSADLYLKLAEVYVKQQNWTLALETVEFALKSNPRNAQLIR--- 500
            .|:|....| ..|    :..:..|..||..:  |.|..|.:.||:.....|..:|.|.:|.|
Frog   207 EAVSRFRGSYGNWRTEDEGSLEEALDYLAFS--YYKAGNISHALDLSRECLLYDPDNGRLARNIA 269

  Fly   501 MQKRLSYHILLGPPKSPKLNIENNDYRLR-------KNGSLY--------------------CFY 538
            ..:::.|       :||..:.:..:.:|:       |...||                    |.|
Frog   270 KYEQILY-------ESPTADADAEEMKLQRPNVTHLKTRDLYEGLCQTLGSQPTSYEDPHMSCMY 327

  Fly   539 DTKIRTFYSLLAPIKAEVLFIDPLVILYHE 568
            ||.... |.||.|:|.|::.:.|.|:|||:
Frog   328 DTNSHP-YLLLQPMKKEIVSLRPQVVLYHD 356

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34041	NP_001034077.5	P4Ha_N	29..138	CDD:285528
		P4Ha_N	260..389	CDD:285528	28/139 (20%)
		TPR repeat	452..491	CDD:276809	11/43 (26%)
p4ha3	XP_031752143.1	P4Ha_N	35..>104	CDD:400573	14/78 (18%)
		TPR repeat	182..210	CDD:276809	9/27 (33%)
		TPR repeat	215..257	CDD:276809	11/43 (26%)
		P4Hc	359..531	CDD:214780
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000