DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Octbeta3R and taar11

DIOPT Version :9

Sequence 1:	NP_001034048.2	Gene:	Octbeta3R / 3885573	FlyBaseID:	FBgn0250910	Length:	1256	Species:	Drosophila melanogaster
Sequence 2:	NP_001076546.1	Gene:	taar11 / 794647	ZFINID:	ZDB-GENE-041014-52	Length:	327	Species:	Danio rerio

Alignment Length:	231	Identity:	64/231 - (27%)
Similarity:	110/231 - (47%)	Gaps:	36/231 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   145 IFSSIILAAVLGNALVIISVQRNRKLRVITNYFVVSLAMADMLVALCAM--TFNASVELSGGKWM 207
            :|...|:..|.||..||.::...::|...|||.::|:|::|:|:....|  :...|:|..   |.
Zfish    40 LFIIAIILIVFGNLWVICTISFFQQLHTPTNYLILSMAVSDLLLGSFVMPPSMLRSLETC---WY 101

  Fly   208 FGPFMCNVYNSLDVYFSTASILHLCCISVDRYYAIVRPLEYPLNMTHKTVCFMLANVWILPALIS 272
            ||.|.|..:::.|.....||:|||..||:|||||:.:|..|...||.:...||:...|...|...
Zfish   102 FGDFFCKFHSATDFTLCNASVLHLVFISIDRYYAVCQPFHYQSRMTTRVSVFMILISWSFSAFFG 166

  Fly   273 FTPIF----LGWYTTEE------------HLREISLHPDQCSFVVNKAYALISSSVSFWIPGIVM 321
            |..||    :....|||            |.|||.:           .|:|    |.:::|..::
Zfish   167 FGIIFSELKIEKKRTEELHVACKGGCLALHGREIGV-----------TYSL----VFYFLPMFII 216

  Fly   322 LVMYWRIFKEAIRQRKALSRTSSNILLNSVHMGHTQ 357
            :.:|.|:|..|::..:.::..:|::....:.:..|:
Zfish   217 VSLYSRVFIIALKHVRVINSAASSLSATKMDLKATK 252

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Octbeta3R	NP_001034048.2	7tm_4	146..>346	CDD:304433	63/217 (29%)
Octbeta3R	NP_001034048.2	7tm_1	156..>344	CDD:278431	59/205 (29%)
taar11	NP_001076546.1	7tmA_TAAR1	49..313	CDD:320438	62/222 (28%)
		TM helix 2	69..95	CDD:320438	8/25 (32%)
		TM helix 3	107..137	CDD:320438	14/29 (48%)
		TM helix 4	149..172	CDD:320438	6/22 (27%)
		TM helix 5	197..226	CDD:320438	10/43 (23%)
		TM helix 6	245..275	CDD:320438	1/8 (13%)
		TM helix 7	284..309	CDD:320438
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	0	0.000