DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Octbeta3R and LOC563567

DIOPT Version :9

Sequence 1:	NP_001034048.2	Gene:	Octbeta3R / 3885573	FlyBaseID:	FBgn0250910	Length:	1256	Species:	Drosophila melanogaster
Sequence 2:	XP_005158584.1	Gene:	LOC563567 / 563567	-ID:	-	Length:	447	Species:	Danio rerio

Alignment Length:	279	Identity:	98/279 - (35%)
Similarity:	150/279 - (53%)	Gaps:	31/279 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   117 NGSDIAVD---NQAELEESWLDLSLLLLKGFIFSSIILAAVLGNALVIISVQRNRKLR-VITNYF 177
            ||::...|   ...|.|:.....|:..|.||:...:|::.:|||.||..:|.:.|.|| .:||:|
Zfish     9 NGTNHTQDRAHGAQEREDGDGQNSVRALLGFVLFLLIVSTLLGNTLVCAAVVKFRHLRSKVTNFF 73

  Fly   178 VVSLAMADMLVALCAMTFNASVELSGGKWMFGPFMCNVYNSLDVYFSTASILHLCCISVDRYYAI 242
            |:|||::|:.||:..|.:.| :....|.|:||.| |.::.:.|:..||||||:||.||||||:||
Zfish    74 VISLAVSDLFVAVLVMPWEA-ISAVAGTWLFGRF-CGIWIAFDIMCSTASILNLCIISVDRYWAI 136

  Fly   243 VRPLEYPLNMTHKTVCFMLANVWILPALISFTPIFLGWYTTEEHLREI----SLHPDQCSFVVNK 303
            ..|..|...|||:....|:...|.|..||||.|:.|.|:..::.....    :.:.|.|...:|:
Zfish   137 ASPFRYERKMTHRVAFMMIGVAWTLSILISFIPVQLNWHMADDDEEGAGGNGTDYSDNCKANLNR 201

  Fly   304 AYALISSSVSFWIPGIVMLVMYWRIFKEA---IRQRKALSRTSSNILLNSVHMGHTQQPTSLSYL 365
            .||:.||.:||:||.|:|:..|.|||:.|   ||:..:|.|.          :.|.|     ::.
Zfish   202 TYAISSSLISFYIPVIIMIATYTRIFRIAQTQIRRISSLERA----------VEHAQ-----NHH 251

  Fly   366 HPSDCDLN---ATSAREET 381
            ..:||...   .|:.::||
Zfish   252 QSNDCSNENSLKTTFKKET 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Octbeta3R	NP_001034048.2	7tm_4	146..>346	CDD:304433	82/207 (40%)
Octbeta3R	NP_001034048.2	7tm_1	156..>344	CDD:278431	80/195 (41%)
LOC563567	XP_005158584.1	7tmA_D1-like_dopamine_R	35..336	CDD:320185	92/253 (36%)
		TM helix 1	36..62	CDD:320185	10/25 (40%)
		TM helix 2	70..97	CDD:320185	12/27 (44%)
		TM helix 3	107..137	CDD:320185	17/29 (59%)
		TM helix 4	149..169	CDD:320185	7/19 (37%)
		TM helix 5	200..230	CDD:320185	15/29 (52%)
		TM helix 6	267..297	CDD:320185	2/4 (50%)
		TM helix 7	305..330	CDD:320185
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24248
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010