Protein Alignment Octbeta3R and Octalpha2R

DIOPT Version :9

• Sequence 1: NP_001034048.2
• Gene: Octbeta3R / 3885573
• FlyBaseID: FBgn0250910
• Length: 1256
• Species: Drosophila melanogaster
• Sequence 2: NP_001262715.1
• Gene: Octalpha2R / 42258
• FlyBaseID: FBgn0038653
• Length: 740
• Species: Drosophila melanogaster
• Alignment Length: 1255
• Identity: 234/1255 - (18%)
• Similarity: 358/1255 - (28%)
• Gaps: 586/1255 - (46%)

  Fly    38 SHLQPATLTGHISTT--AAAKTTTTPTS--------------SLPITSQFVDASLTSLSLTATSS 86
            |.|.....||:|||.  .|..:|..|.:              :||..|.:|:.:.|...|..:..
  Fly     4 SRLNANINTGNISTDDFLAVFSTGKPDNATLNPPLLSVDGQLTLPPGSGYVNVNDTIFFLNGSFY 68

  Fly    87 DASYSSPFSSYLSSDSTFELLSTVGPNITANGSDIAVDNQAELEESWLDLSLLLLKGFIFSSIIL 151
            ::|.......|..|.::.   :|.|.....|.:::..|.:   ..|...|:.:::...|.:.:::
  Fly    69 NSSLQLAAGFYNQSSASG---ATSGNLTNPNHTEVHWDGR---YPSGYTLTHIVIASIIVTILMI 127

  Fly   152 AAVLGNALVIISVQRNRKLRVITNYFVVSLAMADMLVALCAMTFNASVELSGGKWMFGPFMCNVY 216
            ..|:||.||||::...:.|:.|.|:|:.|||:||..:.|..|.|:.:.||. |.|:||.:.|:::
  Fly   128 IIVVGNMLVIIAIATEKSLKNIQNWFIASLAVADFFLGLIIMPFSLANELM-GYWIFGSWWCDIH 191

  Fly   217 NSLDVYFSTASILHLCCISVDRYYAIVRPLEYPLNMTHKTVCFMLANVWILPALISFTPIFLGWY 281
            :::||...||||::||.||:|||::|.:.::|..:.|......|:..|||:.|||...|: |||
  Fly   192 SAMDVLLCTASIMNLCLISLDRYWSITKAVDYLKSRTPARAAVMITAVWIMSALICIPPL-LGW- 254

  Fly   282 TTEEHLREISLHPD----QCSFVVNKAYALISSSVSFWIPGIVMLVMYWRI-FKEAIRQRKALSR 341
                   ::.: |:    :|....:..|.|.|:..||:||..:|:.:|.|| |....|.|:.:
  Fly   255 -------KVKM-PEGPLPKCELSEDIGYVLYSALGSFYIPSCIMVFVYIRIYFAAKARARRGI-- 309

  Fly   342 TSSNILLNSVHMGHTQQPTSLSYLHPSDCDLNATSAREETHSALSNLEDMLQPATDEDDDRDECD 406
                                                                             
  Fly   310 ----------------------------------------------------------------- 309

  Fly   407 ELRVPSPPPRRLSRSSIDLRDLEQERYEKVTHTDSAPSMMALQQQQPSHNQLQPPAPVFNPQIWT 471
                                                                             
  Fly   310 ----------------------------------------------------------------- 309

  Fly   472 EGKMIPSKELDKEHSHPNGPQQQLSLTSGSGNSEPEPESTAYRVFGGLNSDESEGNDLYDTHLPL 536
                       |:|......:|..|.|:....:.|.|.|:
  Fly   310 -----------KKHPRKTNNEQVTSFTTAKKGTIPMPSSS------------------------- 338

  Fly   537 AEDNKELKRLIEDNYLYFKRQTGGTIISGPGGGKYAALSETDFIRLKAGAAACGRKAFASSDSEF 601
                                                                             
  Fly   339 ----------------------------------------------------------------- 338

  Fly   602 LRTISESRALPEQPVPGKEKGFNILSLLSKTKRSSTECFTLEKKRHQANSEGSSFFRRSRNRKLS 666
                                |.:.|.|                  ||
  Fly   339 --------------------GVSALQL------------------HQ------------------ 347

  Fly   667 HSYNGCGGGKERKLERRQRQHSDTDSTPNKPDILLDINVLSEQSGASVIQQFSDGVQLIDFSELK 731
                             |||.:..::.||...:.:.|        .:|....:..:...:..||:
  Fly   348 -----------------QRQIATIETPPNSASLPMQI--------PTVTMDLASDISTSEAGELE 387

  Fly   732 TPPERIRSDDELAQLADCFGESPQQPATPPPSLSPPELPEPSGLLIASSSELAEIFRSLSFPLGR 796
            .                                            :|:.:.||         ...
  Fly   388 A--------------------------------------------VAAQTVLA---------YAN 399

  Fly   797 PAGAPQRLSTLSDQVCANYLMSPPNTPAPPAISVPNGGAMDSSASSNAQSASINVYFLSPPPHAA 861
            |.||                    .|.:...:|..|||                      |..:.
  Fly   400 PNGA--------------------GTNSVTVVSSGNGG----------------------PGASG 422

  Fly   862 APGYTPSDTSTVSLDVVTSLPMPVPVPQPNPQMASQSNISPKPEIILDSTLSPVEGCGDEHRDVT 926
            .|..:|.:|..||......:.:.||||   |.|.|.|:|:     :|::....|.
  Fly   423 VPPSSPKETLQVSTIATGRVGLNVPVP---PSMGSNSSIN-----VLNNNNGTVA---------- 469

  Fly   927 SPLFKRKDSAGDADVSVSGNGGA----GGVGGVGGRQGRCSILAGYDGIQTVRKRQASVVTYDVN 987
                    ..|.|..:..|||.|    ||:...||.:.|.|.:||       |.|..||......
  Fly   470 --------MDGGATAAGGGNGSAVATPGGLQQTGGNELRVSPIAG-------RCRALSVGVDTDM 519

  Fly   988 VINFSQENSDSRSYIPMGRVSTSSAKHEFSNKSSLIRRGGICIFVDEEEAEIIEQRPRGITFAAV 1052
            |..|...:|||                            |:                  ::..||
  Fly   520 VSEFDPSSSDS----------------------------GV------------------VSRCAV 538

  Fly  1053 PSPLP--KC-PLCGADISSTTGTTANATATANADSTIDTTVTTSSKRSIHEQTPDLGQ------R 1108
            ..||.  .| |:.|...|:.........|..|..|:     ..:||....:|.....|      .
  Fly   539 VKPLKFRLCQPIFGRKSSNQQRRNEAKAAAKNQQSS-----GVASKNQQQQQQQQQQQVVKSELE 598

  Fly  1109 PASSSSSTRFWHKRTAAVTACWQQSKNRKRRFKTGCSHCGATGGSVRPAKGWKAEHKAARTLGII 1173
            ||...             |...:..:..|||...                  |.|.:|...||:|
  Fly   599 PAIPK-------------TPKPRDPEKEKRRIAR------------------KKEKRATLILGLI 632

  Fly  1174 MGVFLLCWLPFFLWYVITSLCGPACPCPDVLVVVLFWIGYFNSTLNPLIYAYFNRDFREAFRNTL 1238
            ||.|:.||||||..|::...|...|..|:....|.||:||.||.|||.||..||:|||.|||..|
  Fly   633 MGSFIACWLPFFFLYILVPACSSHCNIPESAFAVAFWLGYMNSALNPAIYTIFNKDFRRAFRRIL 697

  Fly  1239 -----------ECVLPCLEK 1247
                       .||...:||
  Fly   698 FKXCLAYVCCYRCVYASIEK 717

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Octbeta3R	NP_001034048.2	7tm_4	146..>346	CDD:304433	69/204 (34%)
		7tm_1	156..>344	CDD:278431	68/192 (35%)
Octalpha2R	NP_001262715.1	7tm_1	132..>315	CDD:278431	70/336 (21%)
		7tm_4	133..>252	CDD:304433	48/120 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24248
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010