DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Octbeta3R and Taar6

DIOPT Version :9

Sequence 1:	NP_001034048.2	Gene:	Octbeta3R / 3885573	FlyBaseID:	FBgn0250910	Length:	1256	Species:	Drosophila melanogaster
Sequence 2:	NP_783174.1	Gene:	Taar6 / 294124	RGDID:	631384	Length:	345	Species:	Rattus norvegicus

Alignment Length:	257	Identity:	85/257 - (33%)
Similarity:	123/257 - (47%)	Gaps:	42/257 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   138 LLLLKGFIFSSIILAAVLGNALVIISVQRNRKLRVITNYFVVSLAMADMLVALCAMTFN--ASVE 200
            :||...|.|.:::  ||.||.||:||:...::|...||:.:.|||.||..|.:..|.|:  .|:|
  Rat    33 VLLYAVFGFGAVL--AVFGNLLVMISILHFKQLHSPTNFLIASLACADFWVGVSVMPFSMVRSIE 95

  Fly   201 LSGGKWMFGPFMCNVYNSLDVYFSTASILHLCCISVDRYYAIVRPLEYPLNMTHKT--VCFMLAN 263
               ..|.||...|..:...||.|..:|:.||..||:|||.|:..||.||...|...  :|..::
  Rat    96 ---SCWYFGRSFCTFHTCCDVAFCYSSLFHLSFISIDRYIAVTDPLVYPTKFTVSVSGICISIS- 156

  Fly   264 VWILPALISFTPIFLGWYTTEEHLREISLHPDQ------CSFVVNKAYALISSSVSFWIPGIVML 322
             ||||...|....:.|.|.  :.|.|:|   |.      |..|||:.:.|| ..:||.||.:||:
  Rat   157 -WILPLAYSGAVFYTGVYA--DGLEEVS---DAVNCVGGCQVVVNQNWVLI-DFLSFLIPTLVMI 214

  Fly   323 VMYWRIFKEAIRQRKALSRTSSNILLNSVHMGHTQQPTSLSYLHPSDCDLNATSAREETHSA 384
            ::|..||..|.:|.|.:..           :|:..:.:|.||        .|..||.|..:|
  Rat   215 ILYGNIFLVARQQAKKIET-----------VGNKAESSSESY--------KARVARRERKAA 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Octbeta3R	NP_001034048.2	7tm_4	146..>346	CDD:304433	73/209 (35%)
Octbeta3R	NP_001034048.2	7tm_1	156..>344	CDD:278431	70/197 (36%)
Taar6	NP_783174.1	7tmA_TAAR6_8_9	33..322	CDD:320439	85/257 (33%)
		TM helix 1	35..59	CDD:320439	11/25 (44%)
		TM helix 2	68..90	CDD:320439	9/21 (43%)
		TM helix 3	106..128	CDD:320439	7/21 (33%)
		TM helix 4	151..167	CDD:320439	6/17 (35%)
		TM helix 5	195..218	CDD:320439	9/23 (39%)
		TM helix 6	257..279	CDD:320439	1/1 (100%)
		TM helix 7	290..315	CDD:320439
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000