DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Octbeta3R and Drd5

DIOPT Version :9

Sequence 1:	NP_001034048.2	Gene:	Octbeta3R / 3885573	FlyBaseID:	FBgn0250910	Length:	1256	Species:	Drosophila melanogaster
Sequence 2:	NP_036900.1	Gene:	Drd5 / 25195	RGDID:	2523	Length:	475	Species:	Rattus norvegicus

Alignment Length:	257	Identity:	95/257 - (36%)
Similarity:	138/257 - (53%)	Gaps:	34/257 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   145 IFSSIILAAVLGNALVIISVQRNRKLRV-ITNYFVVSLAMADMLVALCAMTFNASVELSGGKWMF 208
            :.:.:|:..:|||.||..::.|:|.||. :||.|:||||::|:.|||..|.:.|..|:: |.|.|
  Rat    44 LLTLLIVWTLLGNVLVCAAIVRSRHLRAKMTNIFIVSLAVSDLFVALLVMPWKAVAEVA-GYWPF 107

  Fly   209 GPFMCNVYNSLDVYFSTASILHLCCISVDRYYAIVRPLEYPLNMTHKTVCFMLANVWILPALISF 273
            |.| |:::.:.|:..||||||:||.||||||:||.||..|...||.:....|:...|.|..||||
  Rat   108 GTF-CDIWVAFDIMCSTASILNLCIISVDRYWAISRPFRYERKMTQRVALVMVGLAWTLSILISF 171

  Fly   274 TPIFLGWY----------------TTEEHLREISLHPDQCSFVVNKAYALISSSVSFWIPGIVML 322
            .|:.|.|:                |..|...|:....:.|...:|:.||:.||.:||:||..:|:
  Rat   172 IPVQLNWHRDKAGSQGQEGLLSNGTPWEEGWELEGRTENCDSSLNRTYAISSSLISFYIPVAIMI 236

  Fly   323 VMYWRIFKEA---IRQRKALSRTSSNILLNSVHMGHTQQPTSLSYLHPSDCDLNATSAREET 381
            |.|.||::.|   ||:..:|.|.:.          |.|...|.....| |..|.| |.::||
  Rat   237 VTYTRIYRIAQVQIRRISSLERAAE----------HAQSCRSRGAYEP-DPSLRA-SIKKET 286

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Octbeta3R	NP_001034048.2	7tm_4	146..>346	CDD:304433	85/219 (39%)
Octbeta3R	NP_001034048.2	7tm_1	156..>344	CDD:278431	83/207 (40%)
Drd5	NP_036900.1	7tm_1	55..354	CDD:278431	93/246 (38%)
		7tm_4	<121..>173	CDD:304433	28/51 (55%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	415..443
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24248
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010