DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Octbeta3R and Adrb1

DIOPT Version :9

Sequence 1:	NP_001034048.2	Gene:	Octbeta3R / 3885573	FlyBaseID:	FBgn0250910	Length:	1256	Species:	Drosophila melanogaster
Sequence 2:	NP_036833.1	Gene:	Adrb1 / 24925	RGDID:	2059	Length:	466	Species:	Rattus norvegicus

Alignment Length:	259	Identity:	89/259 - (34%)
Similarity:	139/259 - (53%)	Gaps:	9/259 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   122 AVDNQAELEESW-LDLSLLLLKGFIFSSIILAAVLGNALVIISVQRNRKLRVITNYFVVSLAMAD 185
            |.:..|.|.:.| ..:.|||      :.|:|..|:||.|||:::.:..:|:.:||.|::|||.||
  Rat    46 ASEGSAPLSQQWTAGMGLLL------ALIVLLIVVGNVLVIVAIAKTPRLQTLTNLFIMSLASAD 104

  Fly   186 MLVALCAMTFNASVELSGGKWMFGPFMCNVYNSLDVYFSTASILHLCCISVDRYYAIVRPLEYPL 250
            :::.|..:.|.|:: :..|:|.:|.|.|.::.|:||...||||..||.|::|||.||..|..|..
  Rat   105 LVMGLLVVPFGATI-VVWGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITLPFRYQS 168

  Fly   251 NMTHKTVCFMLANVWILPALISFTPIFLGWYTTE-EHLREISLHPDQCSFVVNKAYALISSSVSF 314
            .:|......::..||.:.||:||.||.:.|:..| :..|.....|..|.||.|:|||:.||.|||
  Rat   169 LLTRARARALVCTVWAISALVSFLPILMHWWRAESDEARRCYNDPKCCDFVTNRAYAIASSVVSF 233

  Fly   315 WIPGIVMLVMYWRIFKEAIRQRKALSRTSSNILLNSVHMGHTQQPTSLSYLHPSDCDLNATSAR 378
            ::|..:|..:|.|:|:||.:|.|.:.......|.............|.....|:|...|..|::
  Rat   234 YVPLCIMAFVYLRVFREAQKQVKKIDSCERRFLTGPPRPPSPAPSPSPGPPRPADSLANGRSSK 297

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Octbeta3R	NP_001034048.2	7tm_4	146..>346	CDD:304433	76/200 (38%)
Octbeta3R	NP_001034048.2	7tm_1	156..>344	CDD:278431	73/188 (39%)
Adrb1	NP_036833.1	7tm_1	75..366	CDD:278431	79/224 (35%)
		7tm_4	76..>267	CDD:304433	72/191 (38%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	264..302		6/34 (18%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	398..466
		PDZ-Binding. /evidence=ECO:0000250	463..466
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	230	1.000	Domainoid score	I2359
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D328277at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm44908
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24248
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.020