| Sequence 1: | NP_001034048.2 | Gene: | Octbeta3R / 3885573 | FlyBaseID: | FBgn0250910 | Length: | 1256 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_987076.2 | Gene: | Chrm2 / 243764 | MGIID: | 88397 | Length: | 466 | Species: | Mus musculus |
| Alignment Length: | 235 | Identity: | 71/235 - (30%) |
|---|---|---|---|
| Similarity: | 123/235 - (52%) | Gaps: | 26/235 - (11%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 138 LLLLKGFIFSSIILAAVLGNALVIISVQRNRKLRVITNYFVVSLAMADMLVALCAMTFNASVELS 202
Fly 203 GGKWMFGPFMCNVYNSLDVYFSTASILHLCCISVDRYYAIVRPLEYPLNMTHKTVCFMLANVWIL 267
Fly 268 PALISFTPIFLGWY------TTEEHLREISLHPDQC--SFVVNKAYALISSSVSFWIPGIVMLVM 324
Fly 325 YW---RIFKEAIRQRKALSRTSSNILLNSVHMGHTQQPTS 361 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Octbeta3R | NP_001034048.2 | 7tmA_DmOct-betaAR-like | 142..>338 | CDD:320194 | 66/206 (32%) |
| TM helix 1 | 142..167 | CDD:320194 | 8/24 (33%) | ||
| TM helix 2 | 174..200 | CDD:320194 | 9/25 (36%) | ||
| TM helix 3 | 213..243 | CDD:320194 | 12/29 (41%) | ||
| TM helix 4 | 255..278 | CDD:320194 | 7/22 (32%) | ||
| TM helix 5 | 302..331 | CDD:320194 | 10/31 (32%) | ||
| 7tm_GPCRs | <1161..1234 | CDD:475119 | |||
| TM helix 6 | 1167..1189 | CDD:410628 | |||
| TM helix 7 | 1202..1227 | CDD:410628 | |||
| Chrm2 | NP_987076.2 | 7tmA_mAChR_M2 | 24..451 | CDD:320424 | 71/235 (30%) |
| TM helix 1 | 25..51 | CDD:320424 | 9/28 (32%) | ||
| TM helix 2 | 58..84 | CDD:320424 | 9/25 (36%) | ||
| TM helix 3 | 96..126 | CDD:320424 | 12/29 (41%) | ||
| Important for signaling | 120..122 | 1/1 (100%) | |||
| TM helix 4 | 138..161 | CDD:320424 | 7/23 (30%) | ||
| TM helix 5 | 183..212 | CDD:320424 | 9/28 (32%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 218..320 | 4/28 (14%) | |||
| TM helix 6 | 380..410 | CDD:320424 | |||
| TM helix 7 | 419..444 | CDD:320424 | |||
| Important for signaling | 436..440 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||