DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Octbeta3R and C01F1.4

DIOPT Version :9

Sequence 1:	NP_001034048.2	Gene:	Octbeta3R / 3885573	FlyBaseID:	FBgn0250910	Length:	1256	Species:	Drosophila melanogaster
Sequence 2:	NP_494751.1	Gene:	C01F1.4 / 182068	WormBaseID:	WBGene00015299	Length:	333	Species:	Caenorhabditis elegans

Alignment Length:	221	Identity:	52/221 - (23%)
Similarity:	95/221 - (42%)	Gaps:	43/221 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   144 FIFSSIILAAVLG--NALVIISVQRNRKLRVITNYFVVSLAMADMLVALC---AMTFNASVELSG 203
            ||.|.|||..|..  |.:|:|| :...|:|..:.....|||::|...::.   ::.:|:
Worm    13 FIPSIIILCCVAAFLNFMVVIS-RLYCKMRSASLELTYSLALSDTWTSIVIGFSLFWNS------ 70

  Fly   204 GKWMFGPFMCNVYNSLDVY------FSTASIL----HLCCISVDRYYAIVRPLEYPLNMTHKTVC 258
                :.|.:.|:.:|...:      |.|..:|    ||..::...|..|.||.::...:..:|:.
Worm    71 ----YKPVVLNIPHSSYCFPLTLEAFRTGGLLTGIFHLVALAFTHYMTIKRPFDHHKVLPIRTIY 131

  Fly   259 FMLANVWILPALISFTPIFLGWYTTEEHLREISLHPDQC---SFVVNKAY-ALISSSVSFWIPGI 319
            .|:..:|..|      |:.|..|......:  ....::|   .|..|..: ||:|..:.|.|  |
Worm   132 IMIFFMWATP------PMALMIYFASNSGQ--GYQSEKCMGIKFYENFYFRALVSLIIVFLI--I 186

  Fly   320 VMLVMYWRIFKEAIRQRKALSRTSSN 345
            :..:.|.::.::....|   |:|:||
Worm   187 LTTIFYIKMLQKITEVR---SKTASN 209

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Octbeta3R	NP_001034048.2	7tm_4	146..>346	CDD:304433	50/219 (23%)
Octbeta3R	NP_001034048.2	7tm_1	156..>344	CDD:278431	43/206 (21%)
C01F1.4	NP_494751.1	7tm_classA_rhodopsin-like	17..286	CDD:381740	49/217 (23%)
		TM helix 1	17..37	CDD:381740	8/20 (40%)
		TM helix 2	45..69	CDD:381740	4/23 (17%)
		TM helix 3	85..109	CDD:381740	5/23 (22%)
		TM helix 4	132..148	CDD:381740	5/21 (24%)
		TM helix 5	174..193	CDD:381740	6/20 (30%)
		TM helix 6	220..245	CDD:381740
		TM helix 7	261..286	CDD:381740
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910