| Sequence 1: | NP_001034048.2 | Gene: | Octbeta3R / 3885573 | FlyBaseID: | FBgn0250910 | Length: | 1256 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_000667.1 | Gene: | ADORA2B / 136 | HGNCID: | 264 | Length: | 332 | Species: | Homo sapiens |
| Alignment Length: | 290 | Identity: | 80/290 - (27%) |
|---|---|---|---|
| Similarity: | 121/290 - (41%) | Gaps: | 75/290 - (25%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 144 FIFSSIILAA--VLGNALVIISVQRNRKLRVITNYFVVSLAMADMLVALCAMTFNASVELSGGKW 206
Fly 207 MFGPFMCNVYNSL-----DVYFSTASILHLCCISVDRYYAIVRPLEYPLNMTHKTVCFMLANVWI 266
Fly 267 LPALISFTPIFLGWYTTEEHLREISLHPD----------QCSF--VVNKAYALISSSVSFWIPG- 318
Fly 319 IVMLVMYWRIFKEAIRQRKALSRTSSNILLNSVHMGHTQQPTSLSYLHPSDCDLNATSAREETHS 383
Fly 384 ALS------------------NLEDMLQPA 395 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Octbeta3R | NP_001034048.2 | 7tmA_DmOct-betaAR-like | 142..>338 | CDD:320194 | 66/213 (31%) |
| TM helix 1 | 142..167 | CDD:320194 | 8/24 (33%) | ||
| TM helix 2 | 174..200 | CDD:320194 | 14/25 (56%) | ||
| TM helix 3 | 213..243 | CDD:320194 | 10/34 (29%) | ||
| TM helix 4 | 255..278 | CDD:320194 | 6/22 (27%) | ||
| TM helix 5 | 302..331 | CDD:320194 | 8/29 (28%) | ||
| 7tm_GPCRs | <1161..1234 | CDD:475119 | |||
| TM helix 6 | 1167..1189 | CDD:410628 | |||
| TM helix 7 | 1202..1227 | CDD:410628 | |||
| ADORA2B | NP_000667.1 | 7tmA_Adenosine_R_A2B | 8..301 | CDD:320197 | 80/290 (28%) |
| TM helix 1 | 9..35 | CDD:320197 | 8/24 (33%) | ||
| TM helix 2 | 42..69 | CDD:320197 | 14/26 (54%) | ||
| TM helix 3 | 78..108 | CDD:320197 | 9/29 (31%) | ||
| TM helix 4 | 122..140 | CDD:320197 | 4/17 (24%) | ||
| TM helix 5 | 179..209 | CDD:320197 | 8/29 (28%) | ||
| TM helix 6 | 227..257 | CDD:320197 | 5/29 (17%) | ||
| TM helix 7 | 269..294 | CDD:320197 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||