DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Octbeta3R and LOC100490372

DIOPT Version :9

Sequence 1:	NP_001034048.2	Gene:	Octbeta3R / 3885573	FlyBaseID:	FBgn0250910	Length:	1256	Species:	Drosophila melanogaster
Sequence 2:	XP_002937327.2	Gene:	LOC100490372 / 100490372	-ID:	-	Length:	405	Species:	Xenopus tropicalis

Alignment Length:	205	Identity:	80/205 - (39%)
Similarity:	122/205 - (59%)	Gaps:	13/205 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   143 GFIFSSIILAAVLGNALVIISVQRNRKLRVITNYFVVSLAMADMLVALCAMTFNASVELSGGKWM 207
            |.:.:.|.|...||||:|.|.....::||.:|..|::||||||:|||...|.|:...|:: |.|:
Frog    59 GSLLTVIDLITFLGNAVVFICPVVEKRLRTVTYMFIMSLAMADLLVACLVMPFSIIYEVT-GMWL 122

  Fly   208 FGPFMCNVYNSLDVYFSTASILHLCCISVDRYYAIVRPLEYPLNMTHKTVCFMLANVWILPALIS 272
            ||...|.|:.|.||.|.||||:.||.||:|||.::|.|..|...|:.:....|...:|:..:|||
Frog   123 FGKQFCKVWISFDVMFCTASIVTLCFISLDRYCSVVTPYHYSKRMSRRRCIIMTVTIWVYSSLIS 187

  Fly   273 FTPIFLGWYTTEEHLREI-SLHPD---QCSFVVNKAYALISSSVSFWIPGIVMLVMYWRIFKEA- 332
            |.|:..||       .|| .:..|   ||.||.|..:|:::||::|:||.|:|..||:.|::.:
Frog   188 FLPVMQGW-------NEIPGVDTDNGKQCIFVTNWTFAIVASSLAFYIPFIIMCSMYFFIYRASR 245

  Fly   333 IRQRKALSRT 342
            ::..:.:|:|
Frog   246 LKATRIVSQT 255

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Octbeta3R	NP_001034048.2	7tm_4	146..>346	CDD:304433	79/202 (39%)
Octbeta3R	NP_001034048.2	7tm_1	156..>344	CDD:278431	76/192 (40%)
LOC100490372	XP_002937327.2	7tmA_amine_R-like	58..346	CDD:320098	80/205 (39%)
		TM helix 1	58..83	CDD:320098	9/23 (39%)
		TM helix 2	90..117	CDD:320098	13/26 (50%)
		TM helix 3	128..158	CDD:320098	17/29 (59%)
		TM helix 4	170..190	CDD:320098	6/19 (32%)
		TM helix 5	214..270	CDD:320098	14/42 (33%)
		TM helix 6	271..301	CDD:320098
		TM helix 7	311..339	CDD:320098
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D328277at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920