DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Octbeta3R and taar20x

DIOPT Version :9

Sequence 1:	NP_001034048.2	Gene:	Octbeta3R / 3885573	FlyBaseID:	FBgn0250910	Length:	1256	Species:	Drosophila melanogaster
Sequence 2:	XP_017213648.1	Gene:	taar20x / 100150393	ZFINID:	ZDB-GENE-060413-10	Length:	331	Species:	Danio rerio

Alignment Length:	299	Identity:	70/299 - (23%)
Similarity:	118/299 - (39%)	Gaps:	63/299 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   128 ELEESWLDLSLLLLKG---------FIFSSIILA-AVLGNALVIISVQRNRKLRVITNYFVVSLA 182
            |.:..:.|::...:||         ::..|::.| .|..|.|||||:...:||...||..::|||
Zfish     9 ETQYCFPDINSSCVKGRHSSHGYIAYLLVSLLSAWTVFLNLLVIISISHFKKLHTPTNMIILSLA 73

  Fly   183 MADMLVALCAMTFNASVELSGGKWMFGPFMCNVYNSLDVYFSTASILHLCCISVDRYYAIVRPLE 247
            :.|:.:.| .|...| |.|....|.||...||:|....|...:||:.:|..|:||||.|:..||.
Zfish    74 VNDLFIGL-IMPIEA-VRLIETCWYFGDTFCNLYLIFIVILLSASLSNLVLIAVDRYVAVCHPLL 136

  Fly   248 YPLNMTHKTVCFMLANVWILPALISFTPIFLGWYTTEEHLREISLHPDQCSFVVNKAYALISSSV 312
            ||..:|.......:...|:..:......:....|....|...:..  .||..:::.::.:....|
Zfish   137 YPQKITITKTFMCICMCWVCFSAYCTALVINNSYFDPSHRTGVCY--GQCLVLMSFSWTVTDLFV 199

  Fly   313 SFWIPGIVMLVMYWRIF--------------------KEAIRQRKALSR---------------- 341
            .|..|..:::.:|.|||                    .|.:.:||:.|:
Zfish   200 GFIFPCALIITLYLRIFYVVHLQVKVINSLMKGGKSVTENLLKRKSESKAALTLGFIVTVYLLCW 264

  Fly   342 -------------TSSNILLNSVHMGHTQQPTSLSYLHP 367
                         |:.|:|:.:||......|...:..:|
Zfish   265 IPFYICSLTVYSSTAMNVLIWAVHSNSGLNPLVYALFYP 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Octbeta3R	NP_001034048.2	7tm_4	146..>346	CDD:304433	60/249 (24%)
Octbeta3R	NP_001034048.2	7tm_1	156..>344	CDD:278431	57/236 (24%)
taar20x	XP_017213648.1	7tmA_TAARs	32..308	CDD:320183	66/276 (24%)
		TM helix 1	32..58	CDD:320183	9/25 (36%)
		TM helix 2	65..90	CDD:320183	10/26 (38%)
		TM helix 3	102..132	CDD:320183	13/29 (45%)
		TM helix 4	144..167	CDD:320183	1/22 (5%)
		TM helix 5	189..218	CDD:320183	7/28 (25%)
		TM helix 6	244..274	CDD:320183	2/29 (7%)
		TM helix 7	277..302	CDD:320183	6/24 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000