Protein Alignment Octbeta3R and adrb2b

DIOPT Version :10

• Sequence 1: NP_001034048.2
• Gene: Octbeta3R / 3885573
• FlyBaseID: FBgn0250910
• Length: 1256
• Species: Drosophila melanogaster
• Sequence 2: NP_001082940.3
• Gene: adrb2b / 100037315
• ZFINID: ZDB-GENE-070410-32
• Length: 409
• Species: Danio rerio
• Alignment Length: 286
• Identity: 100/286 - (34%)
• Similarity: 148/286 - (51%)
• Gaps: 34/286 - (11%)

  Fly   113 NITA--NGS---DIAVDNQAELEESWLDLSLLLLKGFIFSSIILAAVLGNALVIISVQRNRKLRV 172
            ||:|  |.|   .::|...::.|        ::|...:...::|..|.||||||.::.|.::|:.
Zfish    17 NISAGLNASSPVSLSVSEYSDAE--------VVLISILIGILVLVIVFGNALVISAIVRFQRLQT 73

  Fly   173 ITNYFVVSLAMADMLVALCAMTFNASVELSGGKWMFGPFMCNVYNSLDVYFSTASILHLCCISVD 237
            :||||:.|||.||:::.|..:.|.|...|. ..|.||.|.|..:.:.||...||||..||.|::|
Zfish    74 VTNYFISSLACADLVMGLMVVPFGACYILL-NTWHFGNFFCEFWTATDVLCVTASIETLCVIALD 137

  Fly   238 RYYAIVRPLEYPLNMTHKTVCFMLANVWILPALISFTPIFLGWYTTEEH-----LREISLHPDQC 297
            ||.||:.||.|...:|.:..|.|:..||.:.|||||.||.:.|:.::|.     |.|    |..|
Zfish   138 RYIAIMWPLRYQSMLTKRKACGMVIGVWAVAALISFLPIHMEWWVSDEPEALSCLEE----PTCC 198

  Fly   298 SFVVNKAYALISSSVSFWIPGIVMLVMYWRIFKEAIRQRKALSRTSSNILLNSVHMGHTQQPTSL 362
            .|..|.|||:.||.:||:||.::|..:|.|:|:||.||.:.:.|....|...|:   .||:...:
Zfish   199 DFNTNAAYAVTSSIISFYIPLVIMAFVYSRVFQEARRQLQKIDRIEGRIRTQSL---STQEGNEI 260

  Fly   363 SYLHPSDCDLNATSAREETHSALSNL 388
            .......|        .:.|.||..|
Zfish   261 KNRRTKFC--------MKDHKALKTL 278

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Octbeta3R	NP_001034048.2	7tmA_DmOct-betaAR-like	142..>338	CDD:320194	82/200 (41%)
		TM helix 1	142..167	CDD:320194	8/24 (33%)
		TM helix 2	174..200	CDD:320194	12/25 (48%)
		TM helix 3	213..243	CDD:320194	14/29 (48%)
		TM helix 4	255..278	CDD:320194	11/22 (50%)
		TM helix 5	302..331	CDD:320194	14/28 (50%)
		7tm_GPCRs	<1161..1234	CDD:475119
		TM helix 6	1167..1189	CDD:410628
		TM helix 7	1202..1227	CDD:410628
adrb2b	NP_001082940.3	None