DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34015 and Hint3

DIOPT Version :9

Sequence 1:	NP_001033848.1	Gene:	CG34015 / 3885570	FlyBaseID:	FBgn0054015	Length:	139	Species:	Drosophila melanogaster
Sequence 2:	XP_006512886.1	Gene:	Hint3 / 66847	MGIID:	1914097	Length:	200	Species:	Mus musculus

Alignment Length:	174	Identity:	65/174 - (37%)
Similarity:	91/174 - (52%)	Gaps:	42/174 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 DDNCIFCLISDGRIPSTVL-EVENDDFVIFQDIKPASQHHYLAVTKKHYASLKDLNKSHDSLV-- 64
            |.||:||.::.|:.|.|.| ..||:|.|.|:|||||:.:|||.|.|||..|.|||||.|..:|
Mouse    28 DSNCVFCRVAAGQEPKTELFHCENEDLVCFKDIKPAALYHYLVVPKKHIGSCKDLNKDHIEMVYS 92

  Fly    65 -----------------------QLMENAL--KDLLVSKGVSV---------DDALFGFHLPPFI 95
                                   ::.|..|  .:.:|:.|.::         .|...|||:|||.
Mouse    93 RSVLVAVFTRVWVSLAVLYGTLQRINETRLFRVESMVAAGKTMLERNNFTDFTDVRMGFHVPPFC 157

  Fly    96 TVKHLHMHAISPRTQMTFLSKMIFR-PSVWFKTVDEARIYLSQK 138
            ::.|||:|.|:|..:..||||:::| .|.||.|||    ||.:|
Mouse   158 SISHLHLHVIAPVKEFGFLSKLVYRQDSYWFVTVD----YLLEK 197

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34015	NP_001033848.1	HIT_like	5..106	CDD:294158	48/137 (35%)
Hint3	XP_006512886.1	aprataxin_related	30..168	CDD:238609	48/137 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167837246
Domainoid	1	1.000	106	1.000	Domainoid score	I6584
eggNOG	1	0.900	-	-		E1_COG0537
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H12046
Inparanoid	1	1.050	125	1.000	Inparanoid score	I4680
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG49262
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004937
OrthoInspector	1	1.000	-	-		otm43730
orthoMCL	1	0.900	-	-		OOG6_103575
Panther	1	1.100	-	-	LDO	PTHR12486
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3692
SonicParanoid	1	1.000	-	-		X3479
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.790