DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG34015 and FHIT

DIOPT Version :9

Sequence 1:NP_001033848.1 Gene:CG34015 / 3885570 FlyBaseID:FBgn0054015 Length:139 Species:Drosophila melanogaster
Sequence 2:NP_001159715.1 Gene:FHIT / 2272 HGNCID:3701 Length:147 Species:Homo sapiens


Alignment Length:85 Identity:22/85 - (25%)
Similarity:33/85 - (38%) Gaps:22/85 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly    35 KPASQHHYLAVTKKHYASLKDLNKSHDSLVQLMENALKDLLVSK---GVSVDDALFGFHLPPFI- 95
            ||....|.|.      ..|:.:.:.||    |..:.:.||..:.   |..|:....|..|...: 
Human    29 KPVVPGHVLV------CPLRPVERFHD----LRPDEVADLFQTTQRVGTVVEKHFHGTSLTFSMQ 83

  Fly    96 -------TVKHLHMHAISPR 108
                   ||||:|:|.: ||
Human    84 DGPEAGQTVKHVHVHVL-PR 102

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG34015NP_001033848.1 HIT_like 5..106 CDD:294158 20/81 (25%)
FHITNP_001159715.1 FHIT 5..124 CDD:238606 22/85 (26%)
Histidine triad motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU00464 94..98 2/3 (67%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0537
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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